ArticleNutrition & metabolism2012
Post-metabolic response to passive normobaric hypoxic exposure in sedendary overweight males: a pilot study.
Article in Nutrition & metabolism, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Impact of exercise training in a hypobaric/normobaric hypoxic environment on body composition and glycolipid metabolism in individuals with overweight or obesity: a systematic review and meta-analysis.Frontiers in physiology · 2025Pooled it
- Normobaric hypoxic conditioning in men with metabolic syndrome.Physiological reports · 2018Trial
- Metabolic, Mental and Immunological Effects of Normoxic and Hypoxic Training in Multiple Sclerosis Patients: A Pilot Study.Frontiers in immunology · 2018Trial
- Pilot study on the effects of a 2-week hiking vacation at moderate versus low altitude on plasma parameters of carbohydrate and lipid metabolism in patients with metabolic syndrome.BMC research notes · 2015Trial
- Hypoxic Exercise Alleviates Diabetic Skeletal Myopathy in Zebrafish in Association with Hif1a/Foxo3a Signaling and Mitochondrial Quality Control.International journal of molecular sciences · 2026Article
- Effects of Heat and Hypoxia Training on the Fat Oxidation Capacity of Competitive Athletes.European journal of sport science · 2025Article
- miR-122/PPARβ axis is involved in hypoxic exercise and modulates fatty acid metabolism in skeletal muscle of obese rats.Heliyon · 2024Article
- Mechanisms for Combined Hypoxic Conditioning and Divergent Exercise Modes to Regulate Inflammation, Body Composition, Appetite, and Blood Glucose Homeostasis in Overweight and Obese Adults: A Narrative Review.Sports medicine (Auckland, N.Z.) · 2023Review
- Review
- Influence of acute and chronic intermittent hypoxic-hyperoxic exposure prior to aerobic exercise on cardiovascular risk factors in geriatric patients-a randomized controlled trial.Frontiers in physiology · 2022Article
- The Effects of Intermittent Hypoxic-Hyperoxic Exposures on Lipid Profile and Inflammation in Patients With Metabolic Syndrome.Frontiers in cardiovascular medicine · 2021Article
- Effects of normobaric cyclic hypoxia exposure on mesenchymal stem-cell differentiation-pilot study on bone parameters in elderly.World journal of stem cells · 2020Article
- Effects of strength training under hypoxic conditions on muscle performance, body composition and haematological variables.Biology of sport · 2020Article
- Inhibition of miR-27b Regulates Lipid Metabolism in Skeletal Muscle of Obese Rats During Hypoxic Exercise by Increasing PPARγ Expression.Frontiers in physiology · 2020Article
- Oxygenation of adipose tissue: A human perspective.Acta physiologica (Oxford, England) · 2020Review
- Low Elevation and Physical Inactivity are Associated with a Higher Prevalence of Metabolic Syndrome in Ecuadorian Adults: A National Cross-Sectional Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- Changes in the Paradigm of Traditional Exercise in Obesity Therapy and Application of a New Exercise Modality: A Narrative Review Article.Iranian journal of public health · 2019Review
- Body Composition and Body Weight Changes at Different Altitude Levels: A Systematic Review and Meta-Analysis.Frontiers in physiology · 2019Review
- Exposure and Exercise Training in Hypoxic Conditions as a New Obesity Therapeutic Modality: A Mini Review.Journal of obesity & metabolic syndrome · 2018Review
- High-Intensity Interval Training in Normobaric Hypoxia Leads to Greater Body Fat Loss in Overweight/Obese Women than High-Intensity Interval Training in Normoxia.Frontiers in physiology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelled
backgroundThe present pilot study was designed to test the impact of passive acute normobaric hypoxic exposure (PAH) and passive short-term normobaric hypoxic exposure (PSH) conditions on energy expenditure (EE) and substrates utilisation (glucose and lipid oxidation).
methodsEleven participants have completed the PAH session while the control group (CG) underwent a simulated experimental condition in normobaric normoxic condition. A subset of 6 participants underwent an additional six 3-hour sessions on consecutive days. Metabolic rates were obtained pre- and post-treatments on the morning following an overnight (12 hours) fast in PAH, PSH, and CG groups.
resultsThe statistical outcomes showed a significant increase in EE for PAH, control, and PSH while a shift in substrate utilization towards lipid sources was only detected for PAH and PSH, respectively.
conclusionThis pilot study showed that passive acute normobaric hypoxic exposure did affect EE and fuel utilization in sedentary overweight males and that further passive normobaric hypoxic exposures (PSH) magnified these metabolic adjustments. These outcomes provide valuable information for further research in the area of hypoxia as a new therapeutic strategy to improve the management of weight loss.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.