ArticleNew journal of physics2012
Requirements for contractility in disordered cytoskeletal bundles.
Article in New journal of physics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed.
- Contractile to extensile transitions and mechanical adaptability enabled by activity in cytoskeletal structures.bioRxiv : the preprint server for biology · 2026Article
- Cofilin-mediated actin filament network flexibility facilitates 2D to 3D actomyosin shape change.European journal of cell biology · 2024Article
- Article
- Rapid assembly of a polar network architecture drives efficient actomyosin contractility.Cell reports · 2022Article
- Protein friction and filament bending facilitate contraction of disordered actomyosin networks.Biophysical journal · 2021Article
- Actin-based force generation and cell adhesion in tissue morphogenesis.Current biology : CB · 2021Review
- Intra-bundle contractions enable extensile properties of active actin networks.Scientific reports · 2021Article
- Article
- The Actin Cytoskeleton as an Active Adaptive Material.Annual review of condensed matter physics · 2020Article
- Force Production by a Bundle of Growing Actin Filaments Is Limited by Its Mechanical Properties.Biophysical journal · 2020Article
- Anchoring of actin to the plasma membrane enables tension production in the fission yeast cytokinetic ring.Molecular biology of the cell · 2019Article
- Entropy production rate is maximized in non-contractile actomyosin.Nature communications · 2018Article
- Ultrafast epithelial contractions provide insights into contraction speed limits and tissue integrity.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Spectrin regulates cell contractility through production and maintenance of actin bundles in the Caenorhabditis elegans spermatheca.Molecular biology of the cell · 2018Article
- Nonequilibrium phase diagrams for actomyosin networks.Soft matter · 2018Article
- A disassembly-driven mechanism explains F-actin-mediated chromosome transport in starfish oocytes.eLife · 2018Article
- Filament turnover tunes both force generation and dissipation to control long-range flows in a model actomyosin cortex.PLoS computational biology · 2017Article
- Active force maintains the stability of a contractile ring.The European physical journal. E, Soft matter · 2017Article
- A theory that predicts behaviors of disordered cytoskeletal networks.Molecular systems biology · 2017Article
- Myosin activity drives actomyosin bundle formation and organization in contractile cells of theMolecular biology of the cell · 2017Article
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Authors and funding
3 authors.
Funding
Abstract
Actomyosin contractility is essential for biological force generation, and is well understood in highly organized structures such as striated muscle. Additionally, actomyosin bundles devoid of this organization are known to contract both in vivo and in vitro, which cannot be described by standard muscle models. To narrow down the search for possible contraction mechanisms in these systems, we investigate their microscopic symmetries. We show that contractile behavior requires non-identical motors that generate large-enough forces to probe the nonlinear elastic behavior of F-actin. This suggests a role for filament buckling in the contraction of these bundles, consistent with recent experimental results on reconstituted actomyosin bundles.
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