Evidence map›Paper›PMID 23155191›Full record

ArticleCephalalgia : an international journal of headache2013

Migraine and restless legs syndrome in men.

Anke C Winter, Markus Schürks, Klaus Berger, Julie E Buring, J Michael Gaziano, Tobias Kurth

Open access · greenAbstract read
In one paragraph

Article in Cephalalgia : an international journal of headache, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Pathophysiological Bases of Comorbidity in Migraine.Frontiers in human neuroscience · 2021
    Review
  5. Review
  6. Patterns of gray matter alterations in migraine and restless legs syndrome.Annals of clinical and translational neurology · 2019
    Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Observational
  15. Article
  16. Article
  17. Restless legs syndrome and pain disorders: what's in common?Current pain and headache reports · 2014
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Anke C WinterDivision of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, USA.
Markus Schürks
Klaus Berger
Julie E Buring
J Michael Gaziano
Tobias Kurth
Harvard University · USBrigham and Women's Hospital · USEssen University Hospital · DEUniversité de Bordeaux · FRUniversity of Münster · DE

Funding

Physicians' Health Study II: Prevention Trial of VitaminsR01CA097193 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI GAZIANO, J. MICHAEL · 2002 to 2011
$15.7M
Restless Legs Syndrome, Cardiovascular Risk Factors, and Cardiovascular EventsR01HL091880 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI KURTH, TOBIAS · 2008 to 2010
$1.1M
RANDOMIZED TRIAL OF ASPIRIN AND MORTALITYR01CA040360 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI BURING, JULIE E · 1985 to 2002
$775k
TRIAL OF ASPIRIN AND BETA-CAROTENE IN U S MD'SR01HL034595 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI BURING, JULIE E · 1985 to 1991
–
NCI NIH HHS CA-097193NCI NIH HHS CA-34944NCI NIH HHS CA-40360NCI NIH HHS R01 CA034944NCI NIH HHS R01 CA040360NCI NIH HHS R01 CA097193NHLBI NIH HHS HL-091880NHLBI NIH HHS HL-26490NHLBI NIH HHS HL-34595NHLBI NIH HHS R01 HL026490NHLBI NIH HHS R01 HL034595NHLBI NIH HHS R01 HL091880
6 · The paper itself

Abstract

backgroundPrevious studies suggest an association between migraine and restless legs syndrome (RLS). Population-based data, however, have been limited to women. The aim of this study is to evaluate the association between migraine and RLS in a male cohort.

methodsWe conducted a cross-sectional study among 22,926 participants in the Physicians' Health Study. Migraine and RLS information was self-reported. RLS was classified according to four minimal diagnostic criteria. Age- and multivariable-adjusted logistic regression models were calculated.

resultsOf the 22,926 participants (mean age 67.8), 2816 (12.3%) reported migraine and 1717 (7.5%) RLS. Migraine was associated with an increased multivariable-adjusted odds ratio (OR) (95% confidence interval (CI)) of 1.20 (1.04-1.38) for having RLS. The association remained stable after excluding men with potential mimics of RLS and was not modified by age.

conclusionsResults of our study indicate an association between migraine and RLS in men. The magnitude of effect is similar to what has been reported in women.

Indexed as

AgedComorbidityCross-Sectional StudiesFranceHumansIncidenceMaleMen's HealthMigraine DisordersRestless Legs SyndromeRisk FactorsSex Factors

Identifiers

PMID23155191
PMCPMC3528814
OpenAlexW2014007575

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.