Evidence map›Paper›PMID 23154284›Full record

ReviewVirulence2012

A dendrite in every pie: myeloid dendritic cells in HIV and SIV infection.

Elizabeth R Wonderlich, Simon M Barratt-Boyes

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Virulence, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Elizabeth R WonderlichCenter for Vaccine Research, University of Pittsburgh, Pittsburgh, PA, USA.
Simon M Barratt-Boyes
Institut de Recherche Vaccinale · FRUniversity of Pittsburgh · US

Funding

Training in Cellular & Molecular Mechanisms of Tumor RejectionT32CA082084 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Robert J Binder, Dario AA Vignali · 1999 to 2026
$9.2M
Dendritic Cell Dynamics in Peripheral and Lymphoid Tissues in SIV InfectionR01AI071777 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BARRATT-BOYES, SIMON M · 2007 to 2016
$6.0M
NCI NIH HHS 5T32CA082084-12NCI NIH HHS T32 CA082084NIAID NIH HHS AI071777NIAID NIH HHS AI071777-03S1NIAID NIH HHS R01 AI071777
6 · The paper itself

Abstract

Dendritic cells (DC) are a heterogeneous population of innate immune cells that are fundamental to initiating responses against invading pathogens and regulating immune responses. Myeloid DC (mDC) act as a bridge between the innate and adaptive immune response during virus infections but their role in immunity to human immunodeficiency virus (HIV) remains ill-defined. This review examines aspects of the mDC response to HIV and its simian counterpart, simian immunodeficiency virus (SIV), and emphasizes areas where our knowledge of mDC biology and function is incomplete. Defining the potentially beneficial and detrimental roles mDC play during pathogenic and stable infection of humans and nonhuman primates is crucial to our overall understanding of AIDS pathogenesis.

Indexed as

AnimalsDendritic CellsHIVHIV InfectionsHumansPrimatesSimian Acquired Immunodeficiency SyndromeSimian Immunodeficiency VirusAIDSimmune responseinflammation

Identifiers

PMID23154284
PMCPMC3545946
OpenAlexW1969948313

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.