ReviewThe Journal of clinical investigation2012
TLRs and IFNs: critical pieces of the autoimmunity puzzle.
Review in The Journal of clinical investigation, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Extensive Longitudinal Transverse Myelitis after Influenza A Virus Infection in a Patient with Systemic Lupus Erythematosus.Case reports in rheumatology · 2022Article
- Regulatory role of SphK1 in TLR7/9-dependent type I interferon response and autoimmunity.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020Article
- Association between Type I interferon and depletion and dysfunction of endothelial progenitor cells in C57BL/6 mice deficient in both apolipoprotein E and Fas ligand.Current research in translational medicine · 2018Article
- Article
- Prion-like Aggregation of Mitochondrial Antiviral Signaling Protein in Lupus Patients Is Associated With Increased Levels of Type I Interferon.Arthritis & rheumatology (Hoboken, N.J.) · 2016Article
- Human dendritic cell subsets and function in health and disease.Cellular and molecular life sciences : CMLS · 2015Review
- Suppression of systemic autoimmunity by the innate immune adaptor STING.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Anti-Inflammatory Effect of Combination of Scutellariae Radix and Liriopis Tuber Water Extract.Evidence-based complementary and alternative medicine : eCAM · 2015Article
- Pathogenesis and potential therapeutic targets in systemic lupus erythematosus: from bench to bedside.Auto- immunity highlights · 2014Review
- Autoimmunity versus autoinflammation--friend or foe?Wiener medizinische Wochenschrift (1946) · 2014Review
- The effect of polyamines on the binding of anti-DNA antibodies from patients with SLE and normal human subjects.Clinical immunology (Orlando, Fla.) · 2014Article
- Epstein-Barr virus infection induces aberrant TLR activation pathway and fibroblast-myofibroblast conversion in scleroderma.The Journal of investigative dermatology · 2014Article
- TLR8 on dendritic cells and TLR9 on B cells restrain TLR7-mediated spontaneous autoimmunity in C57BL/6 mice.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- B-lymphocyte tolerance and effector function in immunity and autoimmunity.Immunologic research · 2013Review
- Selective inhibition of spleen tyrosine kinase (SYK) with a novel orally bioavailable small molecule inhibitor, RO9021, impinges on various innate and adaptive immune responses: implications for SYK inhibitors in autoimmune disease therapy.Arthritis research & therapy · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Discoveries revealing the molecular basis of innate immune responses, particularly the identification of Toll-like receptors (TLRs) as the major recognition sensors for microbial and even self-molecules, have provided new insights into the pathogenesis of both systemic and organ-specific autoimmune diseases. These insights will permit the development of novel treatment modalities for these disorders.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.