ArticleBreast cancer research : BCR2012
Migratory gene expression signature predicts poor patient outcome: are cancer stem cells to blame?
Article in Breast cancer research : BCR, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- Pharmacologic Manipulation of Wnt Signaling and Cancer Stem Cells.Methods in molecular biology (Clifton, N.J.) · 2017Review
- Neurotrophin signaling in cancer stem cells.Cellular and molecular life sciences : CMLS · 2016Review
- The Wnt signaling pathway in cancer.Critical reviews in oncology/hematology · 2016Review
- Cancer stem cell plasticity and tumor hierarchy.World journal of stem cells · 2015Review
- Heterogeneity of chemokine cell-surface receptor expression in triple-negative breast cancer.American journal of cancer research · 2015Article
- An agent-based model of cancer stem cell initiated avascular tumour growth and metastasis: the effect of seeding frequency and location.Journal of the Royal Society, Interface · 2014Article
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Abstract
Breast cancer metastasis accounts for the majority of deaths from this disease. In the previous issue of Breast Cancer Research, Patsialou and colleagues used a novel in vivo invasion assay to capture migrating breast cancer cells and demonstrate that the gene expression signature of these cells predicts breast cancer metastasis in a large cohort of patients. Furthermore, specific genes identified play a functional role in the invasion of MDA-MB-231 breast cancer cells and in patient-derived breast tumors. These genes regulate pathways known to be induced in invasion and metastases and play an important role in the regulation of cancer stem cells.
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