ArticleBMC cardiovascular disorders2012
Heart rate variability and target organ damage in hypertensive patients.
Article in BMC cardiovascular disorders, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Heart rate variability as a dual-use digital biomarker: integrating clinical, AI, and operational perspectives on human performance and resilience.BMC cardiovascular disorders · 2026Pooled it
- Associations of Blood Pressure Variability, Heart Rate, and Target Organ Damage in Resistant Hypertension Patients.Journal of clinical hypertension (Greenwich, Conn.) · 2025Article
- Effects of Three-Hour Wearing Personal Protective Equipment on Heart Rate Variability in Healthcare Workers for the Treatment of COVID-19 Patients.International journal of general medicine · 2023Article
- Impact of Water Temperature on Heart Rate Variability during Bathing.Life (Basel, Switzerland) · 2021Article
- Racial Differences in the Influence of Risk Factors in Childhood on Left Ventricular Mass in Young Adulthood.The Journal of pediatrics · 2020Article
- The Autonomic Nervous System and Hypertension: Ethnic Differences and Psychosocial Factors.Current cardiology reports · 2019Review
- Sleep, Autonomic Nervous Function and Atherosclerosis.International journal of molecular sciences · 2019Review
- Impact of heart rate on reproducibility of heart rate variability analysis in the supine and standing positions in healthy men.Clinics (Sao Paulo, Brazil) · 2019Article
- Racial differences in the association between heart rate variability and left ventricular mass.Experimental physiology · 2017Article
- Heart Rate Variability in Patients with Acute Ischemic Stroke at Different Stages of Renal Dysfunction: A Cross-sectional Observational Study.Chinese medical journal · 2017Article
- Automatic messaging for improving patients engagement in diabetes management: an exploratory study.Medical & biological engineering & computing · 2015Article
- Correlation of 24-Hour Blood Pressure and Heart Rate Variability to Renal Function Parameters in Hypertensive Patients. The Effect of Smoking.Journal of clinical hypertension (Greenwich, Conn.) · 2015Article
- Blood Pressure Drop Prediction by using HRV Measurements in Orthostatic Hypotension.Journal of medical systems · 2015Article
- Cloud-Based Smart Health Monitoring System for Automatic Cardiovascular and Fall Risk Assessment in Hypertensive Patients.Journal of medical systems · 2015Observational
- Automatic classifier based on heart rate variability to identify fallers among hypertensive subjects.Healthcare technology letters · 2015Article
- Cardiovascular complications in patients with autonomic failure.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2015Review
- Association between left ventricular mechanics and heart rate variability in untreated hypertensive patients.Journal of clinical hypertension (Greenwich, Conn.) · 2015Article
- Short term Heart Rate Variability to predict blood pressure drops due to standing: a pilot study.BMC medical informatics and decision making · 2015Article
- Automatic prediction of cardiovascular and cerebrovascular events using heart rate variability analysis.PloS one · 2015Article
- User needs elicitation via analytic hierarchy process (AHP). A case study on a Computed Tomography (CT) scanner.BMC medical informatics and decision making · 2013Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe evaluated the association between linear standard Heart Rate Variability (HRV) measures and vascular, renal and cardiac target organ damage (TOD).
methodsA retrospective analysis was performed including 200 patients registered in the Regione Campania network (aged 62.4 ± 12, male 64%). HRV analysis was performed by 24-h holter ECG. Renal damage was assessed by estimated glomerular filtration rate (eGFR), vascular damage by carotid intima-media thickness (IMT), and cardiac damage by left ventricular mass index.
resultsSignificantly lower values of the ratio of low to high frequency power (LF/HF) were found in the patients with moderate or severe eGFR (p-value < 0.001). Similarly, depressed values of indexes of the overall autonomic modulation on heart were found in patients with plaque compared to those with a normal IMT (p-value <0.05). These associations remained significant after adjustment for other factors known to contribute to the development of target organ damage, such as age. Moreover, depressed LF/HF was found also in patients with left ventricular hypertrophy but this association was not significant after adjustment for other factors.
conclusionsDepressed HRV appeared to be associated with vascular and renal TOD, suggesting the involvement of autonomic imbalance in the TOD. However, as the mechanisms by which abnormal autonomic balance may lead to TOD, and, particularly, to renal organ damage are not clearly known, further prospective studies with longitudinal design are needed to determine the association between HRV and the development of TOD.
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