ArticleGenetics, selection, evolution : GSE2012
Optimum contribution selection for conserved populations with historic migration.
Article in Genetics, selection, evolution : GSE, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Targeted allele frequency tuning in breeding populations via alternative optimum contribution selection.Genetics · 2026Article
- Article
- Genomic-Inbreeding Landscape and Selection Signatures in the Polo Argentino Horse Breed.International journal of molecular sciences · 2024Article
- Genomic Characterization of Local Croatian Sheep Breeds-Effective Population Size, Inbreeding & Signatures of Selection.Animals : an open access journal from MDPI · 2024Article
- Pedigree Data from Six Rhesus Macaque (Journal of the American Association for Laboratory Animal Science : JAALAS · 2023Article
- Reintroducing genetic diversity in populations from cryopreserved material: the case of Abondance, a French local dairy cattle breed.Genetics, selection, evolution : GSE · 2023Article
- Selection index theory for populations under directional and stabilizing selection.Genetics, selection, evolution : GSE · 2023Article
- Article
- Evaluation of genetic diversity and management of disease in Border Collie dogs.Scientific reports · 2021Article
- Statistical analysis in support of maintaining a healthy traditional Siamese cat population.Genetics, selection, evolution : GSE · 2021Article
- Implementation of advanced Optimum Contribution Selection in small-scale breeding schemes: prospects and challenges in Vorderwald cattle.Animal : an international journal of animal bioscience · 2020Article
- Article
- Optimum contribution selection for animal breeding and conservation: the R package optiSel.BMC bioinformatics · 2019Article
- Key Genetic Parameters for Population Management.Frontiers in genetics · 2019Article
- Long-Term Impact of Optimum Contribution Selection Strategies on Local Livestock Breeds with Historical Introgression Using the Example of German Angler Cattle.G3 (Bethesda, Md.) · 2017Article
- Novel optimum contribution selection methods accounting for conflicting objectives in breeding programs for livestock breeds with historical migration.Genetics, selection, evolution : GSE · 2017Article
- A unified approach to characterize and conserve adaptive and neutral genetic diversity in subdivided populations.Genetics research · 2014Article
- Advantages of using molecular coancestry in the removal of introgressed genetic material.Genetics, selection, evolution : GSE · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn recent decades, local varieties of domesticated animal species have been frequently crossed with economically superior breeds which has resulted in considerable genetic contributions from migrants. Optimum contribution selection by maximizing gene diversity while constraining breeding values of the offspring or vice versa could eventually lead to the extinction of local breeds with historic migration because maximization of gene diversity or breeding values would be achieved by maximization of migrant contributions. Therefore, other objective functions are needed for these breeds.
resultsDifferent objective functions and side constraints were compared with respect to their ability to reduce migrant contributions, to increase the genome equivalents originating from native founders, and to conserve gene diversity. Additionally, a new method for monitoring the development of effective size for breeds with incomplete pedigree records was applied. Approaches were compared for Vorderwald cattle, Hinterwald cattle, and Limpurg cattle. Migrant contributions could be substantially decreased for these three breeds, but the potential to increase the native genome equivalents is limited.
conclusionsThe most promising approach was constraining migrant contributions while maximizing the conditional probability that two alleles randomly chosen from the offspring population are not identical by descent, given that both descend from native founders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.