Evidence map›Paper›PMID 23152547›Full record

ArticleJournal of clinical microbiology2013

Comparative evaluation of the Nanosphere Verigene RV+ assay and the Simplexa Flu A/B & RSV kit for detection of influenza and respiratory syncytial viruses.

Kevin Alby, Elena B Popowitch, Melissa B Miller

Open access · bronzeAbstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Multiplex PCR system for the rapid diagnosis of respiratory virus infection: systematic review and meta-analysis.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2018
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Performance Characteristics of Xpert Flu/RSV XC Assay.Journal of clinical microbiology · 2015
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Comparison of three commercial RT-PCR systems for the detection of respiratory viruses.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2014
    Article
  13. Review
  14. Article
  15. Review
  16. Rapid diagnosis of influenza: state of the art.Clinics in laboratory medicine · 2014
    Review
  17. Laboratory diagnosis of viral infection.Handbook of clinical neurology · 2014
    Review
  18. Article
  19. Article
  20. Molecular detection of respiratory viruses.Clinics in laboratory medicine · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kevin AlbyClinical Microbiology/Immunology Laboratories, UNC Health Care, Chapel Hill, North Carolina, USA.
Elena B Popowitch
Melissa B Miller
University of North Carolina Health Care · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Using retrospective (n = 200) and prospective (n = 150) nasopharyngeal specimens, we evaluated the Nanosphere Verigene RV+ and the Focus Diagnostics Simplexa Flu A/B & RSV tests. Overall, RV+ demonstrated sensitivities and specificities of 96.6% and 100% for influenza A virus, 100% and 99.7% for influenza B virus, and 100% and 100% for respiratory syncytial virus (RSV), while the Simplexa test sensitivities and specificities were 82.8 and 99.7%, 76.2 and 100%, and 94.6 and 100%, respectively.

Indexed as

Clinical Laboratory TechniquesHumansInfluenza A virusInfluenza B virusInfluenza, HumanNasopharynxProspective StudiesRespiratory Syncytial VirusesRespiratory Syncytial Virus InfectionsRetrospective StudiesSensitivity and SpecificityVirology

Identifiers

PMID23152547
PMCPMC3536264
OpenAlexW1997621351

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.