Evidence map›Paper›PMID 23152204›Full record

SynthesisThe Cochrane database of systematic reviews2012

Continuous and interrupted suturing techniques for repair of episiotomy or second-degree tears.

Christine Kettle, Therese Dowswell, Khaled Mk Ismail

2 registry-linked trialsOpen access · bronzeAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in The Cochrane database of systematic reviews, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 30 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 9 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02582580 nacompletednot on this mapstarted 2015, after this paper: background citation

Effects of Perineal Massage, Vaginal Dilator and Pelvic Floor Muscles Training on the Perineal Integrity Primiparous: A Randomized Controlled Trial Protocol

TypeinterventionalSponsorUniversidade Federal de Sao CarlosRan2015 to 2017Enrolled63ConditionsPregnancyArmsPerineal massage, Vaginal Dilator, Pelvic floor muscles training
NCT03983343 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Skin Glues Compared to Running Sutures for Perineal Skin Repair After Vaginal Delivery. A Randomized Controlled Trial

TypeinterventionalSponsorHaEmek Medical Center, IsraelRan2019 to 2024Enrolled182ConditionsPerineal TearArmsexofin®
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 9 syntheses or guidelines pooled it, 211 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Aspirin (single dose) for perineal pain in the early postpartum period.The Cochrane database of systematic reviews · 2020
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Antibiotic prophylaxis for episiotomy repair following vaginal birth.The Cochrane database of systematic reviews · 2017
    Pooled it
  7. Aspirin (single dose) for perineal pain in the early postpartum period.The Cochrane database of systematic reviews · 2017
    Pooled it
  8. Continuous versus interrupted skin sutures for non-obstetric surgery.The Cochrane database of systematic reviews · 2014
    Pooled it
  9. Pooled it
  10. Trial
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. Trial
  16. Article
  17. Clinical guidance paper VVOG-CRGOLFB prevention and management of obstetrical perineal trauma.European journal of obstetrics & gynecology and reproductive biology: X · 2025
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Christine KettleStaffordshire University, Beaconside, UK. c.kettle@staffs.ac.uk
Therese Dowswell
Khaled Mk Ismail
Liverpool Womens NHS Foundation Trust · GBUniversity of Birmingham · GBUniversity of Staffordshire · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMillions of women worldwide undergo perineal suturing after childbirth and the type of repair may have an impact on pain and healing. For more than 70 years, researchers have been suggesting that continuous non-locking suture techniques for repair of the vagina, perineal muscles and skin are associated with less perineal pain than traditional interrupted methods.

objectivesTo assess the effects of continuous versus interrupted absorbable sutures for repair of episiotomy and second-degree perineal tears following childbirth. SEARCH

methodsWe searched the Cochrane Pregnancy and Childbirth Group's Trials Register (20 January 2012). SELECTION CRITERIA: Randomised trials examining continuous and interrupted suturing techniques for repair of episiotomy and second-degree tears after vaginal delivery. DATA COLLECTION AND ANALYSIS: Three review authors independently assessed trial quality. Two of the three authors independently extracted data and a third review author checked them. We contacted study authors for additional information. MAIN

resultsSixteen studies, involving 8184 women at point of entry, from eight countries, were included. The trials were heterogeneous in respect of operator skill and training. Meta-analysis showed that continuous suture techniques compared with interrupted sutures for perineal closure (all layers or perineal skin only) are associated with less pain for up to 10 days' postpartum (risk ratio (RR) 0.76; 95% confidence interval (CI) 0.66 to 0.88, nine trials). There was an overall reduction in analgesia use associated with the continuous subcutaneous technique versus interrupted stitches for repair of perineal skin (RR 0.70; 95% CI 0.59 to 0.84). There was also a reduction in suture removal in the continuous suturing groups versus interrupted (RR 0.56; 95% CI 0.32 to 0.98), but no significant differences were seen in the need for re-suturing of wounds or long-term pain. AUTHORS'

conclusionsThe continuous suturing techniques for perineal closure, compared with interrupted methods, are associated with less short-term pain, need for analgesia and suture removal. Furthermore, there is also some evidence that the continuous techniques used less suture material as compared with the interrupted methods (one packet compared to two or three packets, respectively).

Indexed as

EpisiotomySuture TechniquesAnalgesicsDelivery, ObstetricFemaleHumansObstetric Labor ComplicationsPerineumPregnancyRandomized Controlled Trials as TopicAnalgesics

Identifiers

PMID23152204
PMCPMC7045987
OpenAlexW1668724028

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.