Evidence map›Paper›PMID 23151941›Full record

ArticleUltrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology2013

Evaluation of cervical stiffness during pregnancy using semiquantitative ultrasound elastography.

E Hernandez-Andrade, S S Hassan, H Ahn, S J Korzeniewski, L Yeo, T Chaiworapongsa, R Romero

Open access · greenAbstract readEvaluation Study
In one paragraph

Article in Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 132 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Recommendations for strain elastography of the uterine cervix.Archives of gynecology and obstetrics · 2024
    Review
  5. Article
  6. Article
  7. Menstrual Pain and Elasticity of Uterine Cervix.Journal of clinical medicine · 2021
    Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
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  18. Shear wave elastography of the maternal cervix: A transabdominal technique.Australasian journal of ultrasound in medicine · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

E Hernandez-AndradePerinatology Research Branch, NICHD/NIH/DHHS, Bethesda, MD, USA. ehernand@med.wayne.edu
S S Hassan
H Ahn
S J Korzeniewski
L Yeo
T Chaiworapongsa
R Romero
United States Department of Health and Human Services · USEunice Kennedy Shriver National Institute of Child Health and Human Development · USWayne State University · US

Funding

The Role Of Subclinical Infection And Cytokines In Preterm ParturitionZIAHD002400 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI ROMERO, ROBERTO · 2009 to 2025
$254.4M
Prenatal Diagnosis Of Congenital AnomaliesZIAHD002401 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI ROMERO, ROBERTO · 2009 to 2025
$81.1M
Intramural NIH HHS ZIA HD002400
6 · The paper itself

Abstract

objectiveTo evaluate cervical stiffness during pregnancy using ultrasound-derived elastography, a method used to estimate the average tissue displacement (strain) within a defined region of interest when oscillatory compression is applied.

methodsStrain was calculated in two regions of interest, the endocervical canal and the entire cervix, from three anatomical planes of the cervix: mid-sagittal in the plane used for cervical length measurement and in cross-sectional planes located at the internal and external cervical os. Associations between strain values, method of ascertainment and patient characteristics were assessed using linear mixed models to account for within-subject correlation. Inter-rater agreement in defining the degree of cervical stiffness was evaluated in 120 regions of interest acquired by two operators in 20 patients.

resultsA total of 1557 strain estimations were performed in 262 patients at 8-40 weeks of gestation. Adjusting for other sources of variation, (1) cervical tissue strain estimates obtained in the endocervical canal were on average 33% greater than those obtained in the entire cervix; (2) measurements obtained in the cross-sectional plane of the external cervical os and sagittal plane were 45% and 13% greater than those measured in the cross-sectional plane of the internal cervical os, respectively; (3) mean strain rates were 14% and 5% greater among parous women with and without a history of preterm delivery compared with those of nulliparous women, respectively, and were on average 13% greater among women with a cervical length of between 25 and 30 mm compared to those with a cervical length of > 30 mm; and (4) cervical tissue strain was more strongly associated with cervical length than with gestational age.

conclusionSemiquantitative elastography can be employed to evaluate changes in cervical stiffness during pregnancy.

Indexed as

AdolescentAdultCervical Length MeasurementCervix UteriElasticityElasticity Imaging TechniquesFemaleHumansObserver VariationParityPregnancyPregnancy TrimestersStress, PhysiologicalUltrasonography, PrenatalYoung Adult

Identifiers

PMID23151941
PMCPMC4161016
OpenAlexW1554403103

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.