Evidence map›Paper›PMID 23151913›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2013

Predictive and prognostic value of metabolic tumour volume and total lesion glycolysis in solid tumours.

Christophe Van de Wiele, Vibeke Kruse, Peter Smeets, Mike Sathekge, Alex Maes

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Prognosis Related to Metastatic Burden Measured by ¹⁸F-Fluorocholine PET/CT in Castration-Resistant Prostate Cancer.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2014
    Trial
  7. Article
  8. Frontiers in immunology · 2026
    Article
  9. Predictive significance ofFrontiers in oncology · 2025
    Article
  10. Clinico-pathological factors and [BMC medical imaging · 2024
    Article
  11. Article
  12. Review
  13. Review on radiomic analysis inCancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Review
  14. Article
  15. Article
  16. Prognostic value of baselineRadiation oncology (London, England) · 2023
    Article
  17. Article
  18. Article
  19. Volumetric parameters from [Journal of neuroendocrinology · 2022
    Observational
  20. Article

22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christophe Van de WieleDepartment of Nuclear Medicine, P7, University Hospital Ghent, De Pintelaan 185-B, 9000 Ghent, Belgium. Christophe.vandewiele@ugent.be
Vibeke Kruse
Peter Smeets
Mike Sathekge
Alex Maes

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Data available in patients suffering from squamous cell carcinoma of the head and neck, lung carcinoma, oesophageal carcinoma and gynaecological malignancies suggest that metabolic tumour volume and to a lesser extent total lesion glycolysis have the potential to become valuable in the imaging of human solid tumours as prognostic biomarkers for short- to intermediate-term survival outcomes, adding value to clinical staging, for assessment of response to treatment with neoadjuvant and concurrent chemotherapy, and for treatment optimization; for example, based on early treatment response assessment using changes in metabolic tumour volume over time, it might be possible to select patients who require a more aggressive treatment to improve their outcome. Prospective studies enrolling consecutive patients, adopting standardized protocols for FDG PET acquisition and processing, adjusting for potential confounders in the analysis (tumour size and origin) and determining the optimal methodology for determination of these novel markers are mandatory.

Indexed as

Carcinoma, Squamous CellDisease-Free SurvivalEsophageal NeoplasmsFemaleFluorodeoxyglucose F18Genital Neoplasms, FemaleGlycolysisHead and Neck NeoplasmsHumansLung NeoplasmsMaleMedical OncologyNeoplasmsNeoplasm StagingPositron-Emission TomographyPredictive Value of TestsFluorodeoxyglucose F18

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.