SynthesisJournal of medical Internet research2012
Persuasive system design does matter: a systematic review of adherence to web-based interventions.
Synthesis in Journal of medical Internet research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 716 papers, 15 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Development and Evaluation of an Ecological Momentary Assessment (EMA) Baseline Screening System for Therapists Who Treat Youths With Depressive Symptoms
Effectiveness of Group Versus Individual Self-management of Depression Using a Mobile App to Increase Treatment Adherence Among Users of a University-based Helpline in the Dominican Republic.
Who cites it
716 citing papers in PubMed, 15 syntheses or guidelines pooled it.
- Persuasive Systems Design Features of Smartphone Apps for Psychosis: Systematic Review.JMIR human factors · 2026Pooled it
- Digital Health Interventions to Promote Physical Activity Among Adolescents: Systematic Review.Journal of medical Internet research · 2026Pooled it
- Effectiveness of Self-Help Interventions to Reduce Work Disability: A Rapid Mixed Methods Systematic Review.Journal of occupational rehabilitation · 2026Pooled it
- Exploring psychosocial barriers in digital walking interventions for the chronically ill: a scoping review.Frontiers in psychology · 2026Pooled it
- Interactive Conversational Agents to Improve Dietary Behaviors for Health Promotion: Mixed Systematic Review.Journal of medical Internet research · 2025Pooled it
- Understanding Adherence to Digital Health Technologies: Systematic Review of Predictive Factors.Journal of medical Internet research · 2025Pooled it
- Mapping the Landscape of Digital Health Intervention Strategies: 25-Year Synthesis.Journal of medical Internet research · 2025Pooled it
- User Experiences of and Preferences for Self-Guided Digital Interventions for the Treatment of Mild to Moderate Eating Disorders: Systematic Review and Metasynthesis.JMIR mental health · 2025Pooled it
- Digital Interventions for Symptoms of Borderline Personality Disorder: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2024Pooled it
- Pooled it
- Acceptability of Digital Mental Health Interventions for Depression and Anxiety: Systematic Review.Journal of medical Internet research · 2024Pooled it
- Engaging Parents in Technology-Assisted Interventions for Childhood Adversity: Systematic Review.Journal of medical Internet research · 2024Pooled it
- The Effectiveness of Strategies to Improve User Engagement With Digital Health Interventions Targeting Nutrition, Physical Activity, and Overweight and Obesity: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2023Pooled it
- Are digital health interventions valuable to support patients with cancer and caregivers? An umbrella review of web-based and app-based supportive care interventions.Cancer medicine · 2023Pooled it
- The effect of forming implementation intentions on alcohol consumption: A systematic review and meta-analysis.Drug and alcohol review · 2023Pooled it
- Identifying Active Ingredients that Cause Change in Digital Parent Training Programs for Child Behavior Problems: A Qualitative Exploration.Child psychiatry and human development · 2026Trial
- Results of the AiM, PLan, and act on LIFestYles (AMPLIFY) Weight Loss Intervention Among Survivors of Obesity-Related Cancers: A Randomized Clinical Trial.Journal of the National Comprehensive Cancer Network : JNCCN · 2026Trial
- Information and communications technology-based versus handout-based home exercise programs for heel pain syndrome: a prospective randomized study.Scientific reports · 2026Trial
- Reducing gambling harm through digital self-help intervention: a pilot study in mild to moderate gambling disorder.Harm reduction journal · 2026Trial
- A randomized trial of two online platforms for dementia family caregivers: GamePlan4Care and Resources4Care.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Trial
656 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough web-based interventions for promoting health and health-related behavior can be effective, poor adherence is a common issue that needs to be addressed. Technology as a means to communicate the content in web-based interventions has been neglected in research. Indeed, technology is often seen as a black-box, a mere tool that has no effect or value and serves only as a vehicle to deliver intervention content. In this paper we examine technology from a holistic perspective. We see it as a vital and inseparable aspect of web-based interventions to help explain and understand adherence.
objectiveThis study aims to review the literature on web-based health interventions to investigate whether intervention characteristics and persuasive design affect adherence to a web-based intervention.
methodsWe conducted a systematic review of studies into web-based health interventions. Per intervention, intervention characteristics, persuasive technology elements and adherence were coded. We performed a multiple regression analysis to investigate whether these variables could predict adherence.
resultsWe included 101 articles on 83 interventions. The typical web-based intervention is meant to be used once a week, is modular in set-up, is updated once a week, lasts for 10 weeks, includes interaction with the system and a counselor and peers on the web, includes some persuasive technology elements, and about 50% of the participants adhere to the intervention. Regarding persuasive technology, we see that primary task support elements are most commonly employed (mean 2.9 out of a possible 7.0). Dialogue support and social support are less commonly employed (mean 1.5 and 1.2 out of a possible 7.0, respectively). When comparing the interventions of the different health care areas, we find significant differences in intended usage (p=.004), setup (p<.001), updates (p<.001), frequency of interaction with a counselor (p<.001), the system (p=.003) and peers (p=.017), duration (F=6.068, p=.004), adherence (F=4.833, p=.010) and the number of primary task support elements (F=5.631, p=.005). Our final regression model explained 55% of the variance in adherence. In this model, a RCT study as opposed to an observational study, increased interaction with a counselor, more frequent intended usage, more frequent updates and more extensive employment of dialogue support significantly predicted better adherence.
conclusionsUsing intervention characteristics and persuasive technology elements, a substantial amount of variance in adherence can be explained. Although there are differences between health care areas on intervention characteristics, health care area per se does not predict adherence. Rather, the differences in technology and interaction predict adherence. The results of this study can be used to make an informed decision about how to design a web-based intervention to which patients are more likely to adhere.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.