ArticleCurrent protocols in protein science2012
Sample preparation, data collection, and preliminary data analysis in biomolecular solution X-ray scattering.
Article in Current protocols in protein science, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed.
- On the Role of Starchy Grains in Ice Nucleation Processes.ACS food science & technology · 2024Article
- Role of Domain-Domain Interactions on the Self-Association and Physical Stability of Monoclonal Antibodies: Effect of pH and Salt.The journal of physical chemistry. B · 2023Article
- Mid-infrared chemical imaging of intracellular tau fibrils using fluorescence-guided computational photothermal microscopy.Light, science & applications · 2023Article
- Effects of Monovalent Salt on Protein-Protein Interactions of Dilute and Concentrated Monoclonal Antibody Formulations.Antibodies (Basel, Switzerland) · 2022Article
- The Interplay between Molten Globules and Heme Disassociation Defines Human Hemoglobin Disassembly.Biophysical journal · 2020Article
- Biochemical and structural characterization of two variants of uncertain significance in the PMS2 gene.Human mutation · 2019Article
- Consensus Bayesian assessment of protein molecular mass from solution X-ray scattering data.Scientific reports · 2018Article
- Self-association of a highly charged arginine-rich cell-penetrating peptide.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Development of tools to automate quantitative analysis of radiation damage in SAXS experiments.Journal of synchrotron radiation · 2017Article
- Preparing monodisperse macromolecular samples for successful biological small-angle X-ray and neutron-scattering experiments.Nature protocols · 2016Article
- Hybrid Approaches to Structural Characterization of Conformational Ensembles of Complex Macromolecular Systems Combining NMR Residual Dipolar Couplings and Solution X-ray Scattering.Chemical reviews · 2016Review
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Abstract
In addition to the classic methods of structural biology--X-ray crystallography and NMR--solution X-ray scattering (SAXS) is playing an increasingly important role in structural investigation of biological macromolecules. However, the simultaneous ease of SAXS data collection and sophistication of its data analysis tools can present challenges to the investigator. Any sample, whether pure or contaminated, whether monodisperse or polydisperse, will yield scattering data, and it is up to the user to ensure the absence of artifacts and to choose a proper structural modeling strategy. This unit discusses experimental aspects of X-ray solution scattering, including sample preparation and data collection, as well as the steps in data processing and preliminary analysis required to ensure the absence of artifacts. The goal is to summarize everything than can go wrong with SAXS data measurement so the user can have confidence in the data before undertaking structural modeling.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.