Variant TREM2 as risk factor for Alzheimer's disease.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

67 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. Genetic Variability in Molecular Pathways Implicated in Alzheimer's Disease: A Comprehensive Review.Frontiers in aging neuroscience · 2021
   Pooled it
2. SIGEL: a context-aware genomic representation learning framework for spatial genomics analysis.Genome biology · 2025
   Article
3. Histology image analysis of 13 healthy tissues reveals molecular-histological correlations.Scientific reports · 2025
   Article
4. Microglial MS4A4A Protects against Epileptic Seizures in Alzheimer's Disease.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
   Article
5. Knockdown ofJournal of inflammation research · 2024
   Article
6. Neuroinflammation represents a common theme amongst genetic and environmental risk factors for Alzheimer and Parkinson diseases.Journal of neuroinflammation · 2022
   Review
7. Role of Impaired Mitochondrial Dynamics Processes in the Pathogenesis of Alzheimer's Disease.International journal of molecular sciences · 2022
   Review
8. CD33 rs2455069 SNP: Correlation with Alzheimer's Disease and Hypothesis of Functional Role.International journal of molecular sciences · 2022
   Article
9. Machine learning prediction and tau-based screening identifies potential Alzheimer's disease genes relevant to immunity.Communications biology · 2022
   Article
10. Research progress of the CXCR4 mechanism in Alzheimer's disease.Ibrain · 2022
    Review
11. Metabolic disorder in Alzheimer's disease.Metabolic brain disease · 2021
    Review
12. Apolipoprotein E4 and meningeal lymphatics in Alzheimer disease: a conceptual framework.Molecular psychiatry · 2021
    Review
13. Cerebrospinal Fluid Biomarkers of Alzheimer's Disease: Current Evidence and Future Perspectives.Brain sciences · 2021
    Review
14. Interaction between genetic factors,Journal of oral microbiology · 2020
    Review
15. Investigation of pathology, expression and proteomic profiles in human TREM2 variant postmortem brains with and without Alzheimer's disease.Brain pathology (Zurich, Switzerland) · 2020
    Article
16. Low-Dose Ionizing Radiation Modulates Microglia Phenotypes in the Models of Alzheimer's Disease.International journal of molecular sciences · 2020
    Article
17. Executive Summary of the 2019 International Conference of Korean Dementia Association: Exploring the Novel Concept of Alzheimer's Disease and Other Dementia: a Report from the Academic Committee of the Korean Dementia Association.Dementia and neurocognitive disorders · 2020
    Review
18. Pan-SHIP1/2 inhibitors promote microglia effector functions essential for CNS homeostasis.Journal of cell science · 2020
    Article
19. Study protocol: ASCRIBED: the impact of Acute SystematiC inflammation upon cerebRospinal fluId and blood BiomarkErs of brain inflammation and injury in dementia: a study in acute hip fracture patients.BMC neurology · 2019
    Article
20. In vivo molecular imaging of neuroinflammation in Alzheimer's disease.Journal of neurochemistry · 2019
    Review

7 more citing papers are in PubMed but not listed here.

Corrections and comments

• Commented on by
  TREM2 and neurodegenerative disease.2013
• Comment on
  Variant of TREM2 associated with the risk of Alzheimer's disease.2013
• Comment on
  TREM2 variants in Alzheimer's disease.2013

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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