ArticleThyroid : official journal of the American Thyroid Association2013
Hashimoto's thyroiditis: celebrating the centennial through the lens of the Johns Hopkins hospital surgical pathology records.
Article in Thyroid : official journal of the American Thyroid Association, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 1 of them a synthesis that pooled it.
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80 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Hashimoto Thyroiditis and Mortality in Patients with Differentiated Thyroid Cancer: The National Epidemiologic Survey of Thyroid Cancer in Korea and Meta-Analysis.Endocrinology and metabolism (Seoul, Korea) · 2024Pooled it
- Quantitative Multi-Parameter MRI Evaluation of Hashimoto's Thyroiditis Changes After Dietary Interventions.Medical science monitor : international medical journal of experimental and clinical research · 2025Trial
- Influence of short-term selenium supplementation on the natural course of Hashimoto's thyroiditis: clinical results of a blinded placebo-controlled randomized prospective trial.Journal of endocrinological investigation · 2017Trial
- Ultrasound-based deep learning radiomics with explainable machine learning for predicting benign and malignant thyroid nodules in lymphocytic thyroiditis: a multicenter study.Quantitative imaging in medicine and surgery · 2026Article
- Clinical and Biochemical Predictors of Thyroid Autoantibody Levels in Hashimoto's Thyroiditis.Cureus · 2026Article
- The role of age and antibodies in central regional lymph node metastases of papillary thyroid carcinoma combined with hashimoto's thyroiditis.BMC cancer · 2026Article
- Usefulness of core needle biopsy of thyroid for the diagnosis of IgG4 Hashimoto's thyroiditis.Journal of translational internal medicine · 2026Article
- Hashimoto Thyroiditis and Progression of Papillary Thyroid Cancer: 10-Year Retrospective Cohort Study.JMIR cancer · 2026Article
- Labial-gland artificial intelligence model screening for autoimmune thyroiditis among patients with connective tissue disease.Frontiers in immunology · 2026Article
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- COVID-19 pandemic and thyroid diseases.Frontiers in endocrinology · 2026Article
- Preoperative thyroglobulin antibody concentrations and prediction of papillary thyroid carcinoma recurrence.Endocrine · 2025Article
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- Association ofInternational journal of molecular sciences · 2025Article
- Validation of DNA methylation and transcriptional characteristics in CCL5 and CXCL8 genes in autoimmune thyroiditis with varying iodine levels.Scientific reports · 2025Article
- Construction of the Single-Cell Landscape of Hashimoto's Thyroiditis Tissue and Peripheral Blood by Single-Cell RNA Sequencing.Immunity, inflammation and disease · 2025Article
- Transcriptomic profiling and machine learning reveal novel RNA signatures for enhanced molecular characterization of Hashimoto's thyroiditis.Scientific reports · 2025Article
- Mechanisms underlying the promotion of papillary thyroid carcinoma occurrence and progression by Hashimoto's thyroiditis.Frontiers in endocrinology · 2025Review
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- Hashimoto's thyroiditis is associated with reduced invasiveness in papillary thyroid carcinoma: a propensity score-matched retrospective cohort study.Frontiers in immunology · 2025Article
20 more citing papers are in PubMed but not listed here.
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Abstract
Hashimoto's thyroiditis is now considered the most prevalent autoimmune disease, as well as the most common endocrine disorder. It was initially described in 1912, but only rarely reported until the early 1950s. To celebrate this centennial, we reviewed the surgical pathology archives of the Johns Hopkins hospital for cases of Hashimoto's thyroiditis, spanning the period from May 1889 to October 2012. Approximately 15,000 thyroidectomies were performed at this hospital over 124 years. The first surgical case was reported in 1942, 30 years after the original description. Then, 867 cases of Hashimoto's thyroiditis were seen from 1942 to 2012, representing 6% of all thyroidectomies. Hashimoto's thyroiditis was the sole pathological finding in 462 cases; it accompanied other thyroid pathologies in the remaining 405 cases. The most commonly associated pathology was papillary thyroid cancer, an association that increased significantly during the last two decades. The most common indication for thyroidectomy was a thyroid nodule that was cytologically suspicious for malignancy. Hashimoto's thyroiditis remains a widespread, intriguing, and multifaceted disease of unknown etiology one century after its description. Advances in the understanding of its pathogenesis and preoperative diagnosis will improve recognition and treatment of this disorder, and may one day lead to its prevention.
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