ArticleThe Analyst2013
Toward development of a surface-enhanced Raman scattering (SERS)-based cancer diagnostic immunoassay panel.
Article in The Analyst, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- AI/ML-Assisted SERS Biosensing for Biomolecular Detection: From Direct Spectral Response to Integrated Diagnostic Systems.Biosensors · 2026Review
- Article
- Simple and sensitive galactose monitoring based on capillary SERS sensor.Analytical and bioanalytical chemistry · 2024Article
- Immunoassays: Analytical and Clinical Performance, Challenges, and Perspectives of SERS Detection in Comparison with Fluorescent Spectroscopic Detection.International journal of molecular sciences · 2024Review
- Window into the mind: Advanced handheld spectroscopic eye-safe technology for point-of-care neurodiagnostic.Science advances · 2023Article
- SERS Immunosensors for Cancer Markers Detection.Materials (Basel, Switzerland) · 2023Review
- Review
- Recent Advances in Sandwich SERS Immunosensors for Cancer Detection.International journal of molecular sciences · 2022Review
- Silver Nanoparticle Films Obtained by Convective Self-Assembly for Surface-Enhanced Raman Spectroscopy Analyses of the Pesticides Thiabendazole and Endosulfan.Frontiers in chemistry · 2022Article
- Nanotechnology and Matrix Metalloproteinases in Cancer Diagnosis and Treatment.Frontiers in molecular biosciences · 2022Review
- Dual-enhancement and dual-tag design for SERS-based sandwich immunoassays: evaluation of a metal-metal effect in 3D architecture.Mikrochimica acta · 2021Article
- Geometrically encoded SERS nanobarcodes for the logical detection of nasopharyngeal carcinoma-related progression biomarkers.Nature communications · 2021Article
- SERS-Active Substrate with Collective Amplification Design for Trace Analysis of Pesticides.Nanomaterials (Basel, Switzerland) · 2019Article
- Novel Surface-Enhanced Raman Spectroscopy Techniques for DNA, Protein and Drug Detection.Sensors (Basel, Switzerland) · 2019Review
- Development of quantitative immunochromatographic assay for rapid and sensitive detection of carbohydrate antigen 19-9 (CA 19-9) in human plasma.Journal of pharmaceutical and biomedical analysis · 2017Article
- Flexible and Tunable 3D Gold Nanocups Platform as Plasmonic Biosensor for Specific Dual LSPR-SERS Immuno-Detection.Scientific reports · 2017Article
- Semi-quantitative analysis of multiple chemical mixtures in solution at trace level by surface-enhanced Raman Scattering.Scientific reports · 2017Article
- Surface Plasmon Resonance or Biocompatibility-Key Properties for Determining the Applicability of Noble Metal Nanoparticles.Materials (Basel, Switzerland) · 2017Review
- Calibrant-Free Analyte Quantitation via a Variable Velocity Flow Cell.Analytical chemistry · 2017Article
- Surface-Enhanced Raman Scattering-Based Immunoassay Technologies for Detection of Disease Biomarkers.Biosensors · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Proteomic analyses of readily obtained human fluids (e.g., serum, urine, and saliva) indicate that the diagnosis of complex diseases will be enhanced by the simultaneous measurement of multiple biomarkers from such samples. This paper describes the development of a nanoparticle-based multiplexed platform that has the potential for simultaneous read-out of large numbers of biomolecules. For this purpose, we have chosen pancreatic adenocarcinoma (PA) as a test bed for diagnosis and prognosis. PA is a devastating form of cancer in which an estimated 86% of diagnoses resulted in death in the United States in 2010. The high mortality rate is due, in part, to the asymptomatic development of the disease and the dearth of sensitive diagnostics available for early detection. One promising route lies in the development of a serum biomarker panel that can generate a signature unique to early stage PA. We describe the design and development of a proof-of-concept PA biomarker immunoassay array coupled with surface-enhanced Raman scattering (SERS) as a sensitive readout method.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.