ArticleJournal of cancer epidemiology2012
Patterns of cancer genetic testing: a randomized survey of Oregon clinicians.
Article in Journal of cancer epidemiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Factors Associated With Implementation of Biomarker Testing and Strategies to Improve Its Clinical Uptake in Cancer Care: Systematic Review Using Theoretical Domains Framework.JCO precision oncology · 2025Pooled it
- A theory-informed systematic review of clinicians' genetic testing practices.European journal of human genetics : EJHG · 2018Pooled it
- Primary care providers' cancer genetic testing-related knowledge, attitudes, and communication behaviors: A systematic review and research agenda.Journal of general internal medicine · 2017Pooled it
- Evaluation of an Italian Population-Based Programme for Risk Assessment and Genetic Counselling and Testing for BRCA1/2-Related Hereditary Breast and Ovarian Cancer after 10 Years of Operation: An Observational Study Protocol.Methods and protocols · 2024Article
- Preparing tomorrow's doctors for the genomics era: A nationwide survey of UK medical students.Future healthcare journal · 2024Article
- Knowledge and perceptions of BRCA1/2 genetic testing and needs of diverse women with a personal or family history of breast cancer in South Florida.Journal of community genetics · 2021Article
- Implementing Cancer Genomics in State Health Agencies: Mapping Activities to an Implementation Science Outcome Framework.Public health genomics · 2020Article
- A feasibility study of breast cancer genetic risk assessment in a federally qualified health center.Cancer · 2018Article
- Physician Experiences and Understanding of Genomic Sequencing in Oncology.Journal of genetic counseling · 2018Article
- Article
- Analysis of Advantages, Limitations, and Barriers of Genetic Counseling Service Delivery Models.Journal of genetic counseling · 2016Article
- Aligning policy to promote cascade genetic screening for prevention and early diagnosis of heritable diseases.Journal of genetic counseling · 2015Article
- Article
- Guidance for laboratories performing molecular pathology for cancer patients.Journal of clinical pathology · 2014Review
- Knowledge, attitudes and referral patterns of lynch syndrome: a survey of clinicians in australia.Journal of personalized medicine · 2014Article
- Physicians' attitudes about multiplex tumor genomic testing.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2014Article
- Barriers and motivators for referral of patients with suspected lynch syndrome to cancer genetic services: a qualitative study.Journal of personalized medicine · 2014Article
- Direct-to-Consumer Genetic Testing and Personal Genomics Services: A Review of Recent Empirical Studies.Current genetic medicine reports · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Introduction. Appropriate use of genetic tests for population-based cancer screening, diagnosis of inherited cancers, and guidance of cancer treatment can improve health outcomes. We investigated clinicians' use and knowledge of eight breast, ovarian, and colorectal cancer genetic tests. Methods. We conducted a randomized survey of 2,191 Oregon providers, asking about their experience with fecal DNA, OncoVue, BRCA, MMR, CYP2D6, tumor gene expression profiling, UGT1A1, and KRAS. Results. Clinicians reported low confidence in their knowledge of medical genetics; most confident were OB-GYNs and specialists. Clinicians were more likely to have ordered/recommended BRCA and MMR than the other tests, and OB-GYNs were twice as likely to have ordered/recommended BRCA testing than primary care providers. Less than 10% of providers ordered/recommended OncoVue, fecal DNA, CYP2D6, or UGT1A1; less than 30% ordered/recommended tumor gene expression profiles or KRAS. The most common reason for not ordering/recommending these tests was lack of familiarity. Conclusions. Use of appropriate, evidence-based testing can help reduce incidence and mortality of certain cancers, but these tests need to be better integrated into clinical practice. Continued evaluation of emerging technologies, dissemination of findings, and an increase in provider confidence and knowledge are necessary to achieve this end.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.