ArticleThe Journal of clinical endocrinology and metabolism2013
Association of postburn fatty acids and triglycerides with clinical outcome in severely burned children.
Article in The Journal of clinical endocrinology and metabolism, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Lipidomic profiling reveals time-resolved oxylipin responses to severe burn injury.Lipids in health and disease · 2026Article
- Study on metabolic disorders in rat liver induced by different times after scalds.Biochemistry and biophysics reports · 2025Article
- Decoding burn trauma: biomarkers for early diagnosis of burn-induced pathologies.Biomarker research · 2024Review
- Nonsevere Burn Induces a Prolonged Systemic Metabolic Phenotype Indicative of a Persistent Inflammatory Response Postinjury.Journal of proteome research · 2024Article
- Metabolic response to burn injury: a comprehensive bibliometric study.Frontiers in medicine · 2024Article
- The involvement of the adrenergic nervous system in activating human brown adipose tissue and browning.Hormones (Athens, Greece) · 2022Review
- Article
- Development and Application of Multidimensional Lipid Libraries to Investigate Lipidomic Dysregulation Related to Smoke Inhalation Injury Severity.Journal of proteome research · 2022Article
- Characteristics And Outcome Influence Of Increased Plasma Triglyceride Level In Severely Burned Adult Patients.Annals of burns and fire disasters · 2021Article
- Observational
- The pathogenesis and diagnosis of sepsis post burn injury.Burns & trauma · 2021Review
- A review of potential biomarkers for assessing physical and psychological trauma in paediatric burns.Burns & trauma · 2021Review
- Inhibition of Lipolysis With Acipimox Attenuates Postburn White Adipose Tissue Browning and Hepatic Fat Infiltration.Shock (Augusta, Ga.) · 2020Article
- Current problems in burn hypermetabolism.Current problems in surgery · 2020Review
- Pathophysiological Response to Burn Injury in Adults.Annals of surgery · 2018Article
- Taming the Flames: Targeting White Adipose Tissue Browning in Hypermetabolic Conditions.Endocrine reviews · 2017Review
- The biochemical alterations underlying post-burn hypermetabolism.Biochimica et biophysica acta. Molecular basis of disease · 2017Review
- The P50 Research Center in Perioperative Sciences: How the investment by the National Institute of General Medical Sciences in team science has reduced postburn mortality.The journal of trauma and acute care surgery · 2017Article
- Lipidomic analysis enables prediction of clinical outcomes in burn patients.Scientific reports · 2016Article
- White Adipose Tissue Browning: A Double-edged Sword.Trends in endocrinology and metabolism: TEM · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
contextFree fatty acids (FFAs) and triglycerides (TGs) are altered postburn, but whether these alterations are associated with postburn outcomes is not clear.
objectiveThe aim of the present study was to analyze lipid metabolic profiles in pediatric burn patients and to correlate these profiles with patient outcomes and hospital courses. DESIGN AND
settingWe conducted a prospective cohort study at an academic pediatric hospital burn center. PATIENTS: Our study included 219 pediatric burn patients.
main outcome measuresPatients were stratified according to their plasma TG and FFA levels. Main patient outcomes, such as postburn morbidity and mortality, and clinical metabolic markers were analyzed.
resultsAll groups were similar in demographics and injury characteristics. Patients with elevated TGs had significantly worse clinical outcomes associated with increased acute-phase protein synthesis indicating augmented inflammation and hypermetabolism, whereas increased FFAs did not seem to profoundly alter postburn outcomes.
conclusionsElevated TGs, but not FFAs, postburn are associated with worsened organ function and clinical outcomes.
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Registered trials
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