ArticleProceedings of the National Academy of Sciences of the United States of America2012
McClintock's challenge in the 21st century.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed.
- Cancer Genes: Origins and Directions.Viruses · 2026Review
- The regulatory potential of transposable elements in maize.Nature plants · 2025Article
- Transcriptional repression in stochastic gene expression, patterning, and cell fate specification.Developmental biology · 2022Article
- Corticosterone dynamically regulates retrotransposable element expression in the rat hippocampus and C6 cells.Neurobiology of stress · 2021Article
- Rapid evolution and conserved function of the piRNA pathway.Open biology · 2019Review
- Construction and Optimization of a Large Gene Coexpression Network in Maize Using RNA-Seq Data.Plant physiology · 2017Article
- Dispersal of an ancient retroposon in the TP53 promoter of Bovidae: phylogeny, novel mechanisms, and potential implications for cow milk persistency.BMC genomics · 2015Article
- Control of Transposon-Mediated Directed Mutation by the Escherichia coli Phosphoenolpyruvate:Sugar Phosphotransferase System.Journal of molecular microbiology and biotechnology · 2015Review
- Barbara McClintock and the discovery of jumping genes.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In 1950, Barbara McClintock published a Classic PNAS article, "The origin and behavior of mutable loci in maize," which summarized the evidence leading to her discovery of transposition. The article described a number of genome alterations revealed through her studies of the Dissociation locus, the first mobile genetic element she identified. McClintock described the suite of nuclear events, including transposon activation and various chromosome aberrations and rearrangements, that unfolded in the wake of genetic crosses that brought together two broken chromosomes 9. McClintock left future generations with the challenge of understanding how genomes respond to genetic and environmental stresses by mounting adaptive responses that frequently include genome restructuring.
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Registered trials
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