ArticleProceedings of the National Academy of Sciences of the United States of America2012
Implantable, multifunctional, bioresorbable optics.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Use of bioresorbable fibers for short-wave infrared spectroscopy using time-domain diffuse optics.Biomedical optics express · 2024Article
- A Silk-Based Platform to Stabilize Phenylalanine Ammonia-lyase for Orally Administered Enzyme Replacement Therapy.Molecular pharmaceutics · 2022Article
- Silk Embolic Material for Catheter-Directed Endovascular Drug Delivery.Advanced materials (Deerfield Beach, Fla.) · 2022Article
- Functionalized Mouth-Conformable Interfaces for pH Evaluation of the Oral Cavity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Article
- Silk fibroins in multiscale dimensions for diverse applications.RSC advances · 2020Review
- Nature-derived materials for the fabrication of functional biodevices.Materials today. Bio · 2020Review
- Evolution of Wearable Devices with Real-Time Disease Monitoring for Personalized Healthcare.Nanomaterials (Basel, Switzerland) · 2019Review
- Electronic and Thermal Properties of Graphene and Recent Advances in Graphene Based Electronics Applications.Nanomaterials (Basel, Switzerland) · 2019Review
- Programmable Vanishing Multifunctional Optics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2019Article
- Polymeric biomaterials for biophotonic applications.Bioactive materials · 2018Review
- Biocompatible and Implantable Optical Fibers and Waveguides for Biomedicine.Materials (Basel, Switzerland) · 2018Review
- Colored and fluorescent nanofibrous silk as a physically transient chemosensor and vitamin deliverer.Scientific reports · 2017Article
- Deformable and conformal silk hydrogel inverse opal.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Evaluation of the Spectral Response of Functionalized Silk Inverse Opals as Colorimetric Immunosensors.ACS applied materials & interfaces · 2016Article
- Bioabsorbable polymer optical waveguides for deep-tissue photomedicine.Nature communications · 2016Article
- Silk-Its Mysteries, How It Is Made, and How It Is Used.ACS biomaterials science & engineering · 2015Article
- Silk-based resorbable electronic devices for remotely controlled therapy and in vivo infection abatement.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- All-water-based electron-beam lithography using silk as a resist.Nature nanotechnology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
Advances in personalized medicine are symbiotic with the development of novel technologies for biomedical devices. We present an approach that combines enhanced imaging of malignancies, therapeutics, and feedback about therapeutics in a single implantable, biocompatible, and resorbable device. This confluence of form and function is accomplished by capitalizing on the unique properties of silk proteins as a mechanically robust, biocompatible, optically clear biomaterial matrix that can house, stabilize, and retain the function of therapeutic components. By developing a form of high-quality microstructured optical elements, improved imaging of malignancies and of treatment monitoring can be achieved. The results demonstrate a unique family of devices for in vitro and in vivo use that provide functional biomaterials with built-in optical signal and contrast enhancement, demonstrated here with simultaneous drug delivery and feedback about drug delivery with no adverse biological effects, all while slowly degrading to regenerate native tissue.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.