ReviewNature reviews. Clinical oncology2012
Functional imaging in adult and paediatric brain tumours.
Review in Nature reviews. Clinical oncology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Comparison of Arterial Spin-Labeling and DSC Perfusion MR Imaging in Pediatric Brain Tumors: A Systematic Review and Meta-Analysis.AJNR. American journal of neuroradiology · 2025Pooled it
- Arterial spin labelling and diffusion-weighted imaging in paediatric brain tumours.NeuroImage. Clinical · 2019Pooled it
- Fractal-geometry analysis of pediatric posterior fossa tumors - a preoperative tool for prediction of histopathology.Neurosurgical review · 2026Article
- Accurate Paediatric Brain Tumour Classification Through Improved Quantitative Analysis ofNMR in biomedicine · 2025Article
- Radiomics in glioma: emerging trends and challenges.Annals of clinical and translational neurology · 2025Review
- Ratio maps of T1w/T2w MRI signal intensity do not improve deep-learning segmentation of pediatric brain tumors.PloS one · 2025Article
- Role of Diagnostic Accuracy of Diffusion-Weighted Imaging In Adult Posterior Fossa Tumors - A Prospective Cross-Sectional Study.Journal of pharmacy & bioallied sciences · 2024Article
- Posterior fossa tumors in children: current insights.European journal of pediatrics · 2023Review
- Article
- Imaging in patients with glioblastoma: A national cohort study.Neuro-oncology practice · 2022Article
- Joint EANM/SIOPE/RAPNO practice guidelines/SNMMI procedure standards for imaging of paediatric gliomas using PET with radiolabelled amino acids and [European journal of nuclear medicine and molecular imaging · 2022Article
- Added value of magnetic resonance spectroscopy for diagnosing childhood cerebellar tumours.NMR in biomedicine · 2022Article
- Preliminary Clinical Application of RGD-Containing Peptides as PET Radiotracers for Imaging Tumors.Frontiers in oncology · 2022Review
- The role of Magnetic Resonance Images (MRIs) in coping for patients with brain tumours and their parents: a qualitative study.BMC cancer · 2021Article
- Filtration-Histogram Based Magnetic Resonance Texture Analysis (MRTA) for the Distinction of Primary Central Nervous System Lymphoma and Glioblastoma.Journal of personalized medicine · 2021Article
- European Society for Paediatric Oncology (SIOPE) MRI guidelines for imaging patients with central nervous system tumours.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Review
- Article
- Classification of paediatric brain tumours by diffusion weighted imaging and machine learning.Scientific reports · 2021Article
- A comparison of pseudo-continuous arterial spin labelling and dynamic susceptibility contrast MRI with and without contrast agent leakage correction in paediatric brain tumours.The British journal of radiology · 2019Article
- Engineering and physical sciences in oncology: challenges and opportunities.Nature reviews. Cancer · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Imaging is a key component in the management of brain tumours, with MRI being the preferred modality for most clinical scenarios. However, although conventional MRI provides mainly structural information, such as tumour size and location, it leaves many important clinical questions, such as tumour type, aggressiveness and prognosis, unanswered. An increasing number of studies have shown that additional information can be obtained using functional imaging methods (which probe tissue properties), and that these techniques can give key information of clinical importance. These techniques include diffusion imaging, which can assess tissue structure, and perfusion imaging and magnetic resonance spectroscopy, which measures tissue metabolite profiles. Tumour metabolism can also be investigated using PET, with 18F-deoxyglucose being the most readily available tracer. This Review discusses these methods and the studies that have investigated their clinical use. A strong emphasis is placed on the measurement of quantitative parameters, which is a move away from the qualitative nature of conventional radiological reporting and presents major challenges, particularly for multicentre studies.
Indexed as
Identifiers
23149894What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.