ArticleChromosoma2013
Drosophila SUUR protein associates with PCNA and binds chromatin in a cell cycle-dependent manner.
Article in Chromosoma, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 36 citations in OpenAlex.
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- Super-resolution microscopy reveals stochastic initiation of replication in Drosophila polytene chromosomes.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2022Article
- Translesion DNA synthesis-driven mutagenesis in very early embryogenesis of fast cleaving embryos.Nucleic acids research · 2022Article
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- Effects of Mutations in theCells · 2020Article
- Faint gray bands in Drosophila melanogaster polytene chromosomes are formed by coding sequences of housekeeping genes.Chromosoma · 2020Article
- Flying High-Muscle-Specific Underreplication inGenes · 2020Article
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- Molecular and genetic organization of bands and interbands in the dot chromosome of Drosophila melanogaster.Chromosoma · 2019Article
- Article
- Article
- Article
- Similarity in replication timing between polytene and diploid cells is associated with the organization of the Drosophila genome.PloS one · 2018Article
- Functional dissection of Drosophila melanogaster SUUR protein influence on H3K27me3 profile.Epigenetics & chromatin · 2017Article
- DNA Replication Control DuringGenetics · 2017Review
- Regulatory functions and chromatin loading dynamics of linker histone H1 during endoreplication inGenes & development · 2017Article
- Guanine quadruplex structures localize to heterochromatin.Nucleic acids research · 2016Article
- Understanding replication fork progression, stability, and chromosome fragility by exploiting the Suppressor of Underreplication protein.BioEssays : news and reviews in molecular, cellular and developmental biology · 2015Article
- Tethering of SUUR and HP1 proteins results in delayed replication of euchromatic regions in Drosophila melanogaster polytene chromosomes.Chromosoma · 2015Article
- DNA replication in nurse cell polytene chromosomes of Drosophila melanogaster otu mutants.Chromosoma · 2015Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Drosophila SUUR (Suppressor of UnderReplication) protein was shown to regulate the DNA replication elongation process in endocycling cells. This protein is also known to be the component of silent chromatin in polyploid and diploid cells. To mark the different cell cycle stages, we used immunostaining patterns of PCNA, the main structural component of replication fork. We demonstrate that SUUR chromatin binding is dynamic throughout the endocyle in Drosophila salivary glands. We observed that SUUR chromosomal localization changed along with PCNA pattern and these proteins largely co-localized during the late S-phase in salivary glands. The hypothesized interaction between SUUR and PCNA was confirmed by co-immunoprecipitation from embryonic nuclear extracts. Our findings support the idea that the effect of SUUR on replication elongation depends on the cell cycle stage and can be mediated through its physical interaction with replication fork.
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