ReviewNature reviews. Cardiology2013
Screening for rheumatic heart disease: current approaches and controversies.
Review in Nature reviews. Cardiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03346525 (The GOAL), which is not on this map. Cited by 56 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The GOAL (GwokO Adunu pa Lutino) Trial: Determining the Impact of Penicillin on Latent Rheumatic Heart Disease: A Randomized Controlled Trial in Uganda
Who cites it
56 citing papers in PubMed, 3 syntheses or guidelines pooled it, 126 citations in OpenAlex.
- Pooled it
- Correlation of angiotensin I-converting enzyme gene insertion/deletion polymorphism with rheumatic heart disease: a meta-analysis.Bioscience reports · 2016Pooled it
- Position statement of the World Heart Federation on the prevention and control of rheumatic heart disease.Nature reviews. Cardiology · 2013Guideline
- Global Burden of Rheumatic Heart Disease (1990-2021), Attributable Risk Factors, and Future Projections.JACC. Basic to translational science · 2026Article
- Heart failure in autoimmune rheumatic diseases.Rheumatology international · 2026Review
- Survival and mortality predictors among adults with rheumatic heart disease in ethiopia: a 10-year retrospective cohort study.BMC cardiovascular disorders · 2026Article
- Article
- Article
- Clinical significance and regulatory mechanism of miR-134-5p in rheumatic heart disease.BMC cardiovascular disorders · 2025Article
- Article
- Preferences for Peer Support Amongst Families Engaged in Paediatric Screening Programmes: The Perspectives of Parents Involved in Screening for Type 1 Diabetes in Children Aged 3-13.Health expectations : an international journal of public participation in health care and health policy · 2024Article
- 2023 World Heart Federation guidelines for the echocardiographic diagnosis of rheumatic heart disease.Nature reviews. Cardiology · 2024Review
- Review
- Deep Learning in Heart Sound Analysis: From Techniques to Clinical Applications.Health data science · 2024Review
- Rheumatic Heart Disease in East Africa: A Systematic Review and Meta-Analysis.International journal of rheumatology · 2023Review
- Comparison of approaches to determine echocardiographic outcomes for children with latent rheumatic heart disease.Open heart · 2022Article
- Article
- Echocardiographic Screening for Rheumatic Heart Disease in a Ugandan Orphanage: Feasibility and Outcomes.Children (Basel, Switzerland) · 2022Article
- Standardization of Epidemiological Surveillance of Rheumatic Heart DiseaseOpen forum infectious diseases · 2022Article
- Transcatheter aortic valve implantation in rheumatic aortic stenosis with a functioning mitral prosthesis.Journal of cardiology cases · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rheumatic heart disease (RHD) is a leading cause of cardiac disease among children in developing nations, and in indigenous populations of some industrialized countries. In endemic areas, RHD has long been a target of screening programmes that, historically, have relied on cardiac auscultation. The evolution of portable echocardiographic equipment has changed the face of screening for RHD over the past 5 years, with greatly improved sensitivity. However, concerns have been raised about the specificity of echocardiography, and the interpretation of minor abnormalities poses new challenges. The natural history of RHD in children with subclinical abnormalities detected by echocardiographic screening remains unknown, and long-term follow-up studies are needed to evaluate the significance of detecting these changes at an early stage. For a disease to be deemed suitable for screening from a public health perspective, it needs to fulfil a number of criteria. RHD meets some, but not all, of these criteria. If screening programmes are to identify additional cases of RHD, parallel improvements in the systems that deliver secondary prophylaxis are essential.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.