Evidence map›Paper›PMID 23149746›Full record

ArticleNature communications2012

Genome sequences of wild and domestic bactrian camels.

Bactrian Camels Genome Sequencing and Analysis Consortium, Jirimutu, Zhen Wang, Guohui Ding, Gangliang Chen, Yamin Sun, Zhihong Sun, Heping Zhang, Lei Wang, Surong Hasi and 63 more

Erratum issuedAbstract read
In one paragraph

Article in Nature communications, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 104 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
104citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

104 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Recent Advances in Camel Immunology.Frontiers in immunology · 2020
    Pooled it
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  4. bioRxiv : the preprint server for biology · 2026
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44 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

73 authors.

Bactrian Camels Genome Sequencing and Analysis Consortium
Jirimutu
Zhen Wang
Guohui Ding
Gangliang Chen
Yamin Sun
Zhihong Sun
Heping Zhang
Lei Wang
Surong Hasi
Yan Zhang
Jianmei Li
Yixiang Shi
Ze Xu
Chuan He
Siriguleng Yu
Shengdi Li
Wenbin Zhang
Mijiddorj Batmunkh
Batsukh Ts
Narenbatu
Unierhu
Shirzana Bat-Ireedui
Hongwei Gao
Banzragch Baysgalan
Qing Li
Zhiling Jia
Turigenbayila
Subudenggerile
Narenmanduhu
Zhaoxia Wang
Juan Wang
Lei Pan
Yongcan Chen
Yaichil Ganerdene
Dabxilt
Erdemt
Altansha
Altansukh
Tuya Liu
Minhui Cao
Aruuntsever
Bayart
Hosblig
Fei He
A Zha-ti
Guangyong Zheng
Feng Qiu
Zikui Sun
Lele Zhao
Wenjing Zhao
Baohong Liu
Chao Li
Yunqin Chen
Xiaoyan Tang
Chunyan Guo
Wei Liu
Liang Ming
Temuulen
Aiying Cui
Yi Li
Junhui Gao
Jing Li
Wurentaodi
Shen Niu
Tao Sun
Zhengxiao Zhai
Min Zhang
Chen Chen
Tunteg Baldan
Tuman Bayaer
Yixue Li
He Meng

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bactrian camels serve as an important means of transportation in the cold desert regions of China and Mongolia. Here we present a 2.01 Gb draft genome sequence from both a wild and a domestic bactrian camel. We estimate the camel genome to be 2.38 Gb, containing 20,821 protein-coding genes. Our phylogenomics analysis reveals that camels shared common ancestors with other even-toed ungulates about 55-60 million years ago. Rapidly evolving genes in the camel lineage are significantly enriched in metabolic pathways, and these changes may underlie the insulin resistance typically observed in these animals. We estimate the genome-wide heterozygosity rates in both wild and domestic camels to be 1.0 × 10(-3). However, genomic regions with significantly lower heterozygosity are found in the domestic camel, and olfactory receptors are enriched in these regions. Our comparative genomics analyses may also shed light on the genetic basis of the camel's remarkable salt tolerance and unusual immune system.

Indexed as

AnimalsAnimals, DomesticAnimals, WildAntibodiesBase SequenceBlood GlucoseCamelusCytochrome P-450 Enzyme SystemGenetic VariationGenomeImmunoglobulin Heavy ChainsMaleMolecular Sequence DataAntibodiesBlood GlucoseCytochrome P-450 Enzyme SystemImmunoglobulin Heavy Chains

Identifiers

PMID23149746
PMCPMC3514880

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.