Evidence map›Paper›PMID 23149458›Full record

ArticleHeredity2013

Bayesian methods for estimating GEBVs of threshold traits.

C-L Wang, X-D Ding, J-Y Wang, J-F Liu, W-X Fu, Z Zhang, Z-J Yin, Q Zhang

Abstract read
In one paragraph

Article in Heredity, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
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  8. Review
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  10. Validation of single-step GBLUP genomic predictions from threshold models using the linear regression method: An application in chicken mortality.Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie · 2021
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

8 authors.

C-L WangKey Laboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture of China, Department of Animal Genetics, Breeding and Reproduction, College of Animal Science and Technology, China Agricultural University, Beijing, China.
X-D Ding
J-Y Wang
J-F Liu
W-X Fu
Z Zhang
Z-J Yin
Q Zhang

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Estimation of genomic breeding values is the key step in genomic selection (GS). Many methods have been proposed for continuous traits, but methods for threshold traits are still scarce. Here we introduced threshold model to the framework of GS, and specifically, we extended the three Bayesian methods BayesA, BayesB and BayesCπ on the basis of threshold model for estimating genomic breeding values of threshold traits, and the extended methods are correspondingly termed BayesTA, BayesTB and BayesTCπ. Computing procedures of the three BayesT methods using Markov Chain Monte Carlo algorithm were derived. A simulation study was performed to investigate the benefit of the presented methods in accuracy with the genomic estimated breeding values (GEBVs) for threshold traits. Factors affecting the performance of the three BayesT methods were addressed. As expected, the three BayesT methods generally performed better than the corresponding normal Bayesian methods, in particular when the number of phenotypic categories was small. In the standard scenario (number of categories=2, incidence=30%, number of quantitative trait loci=50, h² = 0.3), the accuracies were improved by 30.4%, 2.4%, and 5.7% points, respectively. In most scenarios, BayesTB and BayesTCπ generated similar accuracies and both performed better than BayesTA. In conclusion, our work proved that threshold model fits well for predicting GEBVs of threshold traits, and BayesTCπ is supposed to be the method of choice for GS of threshold traits.

Indexed as

Models, GeneticQuantitative Trait, HeritableSelection, GeneticAnimalsBayes TheoremBreedingCattleComputer SimulationFemaleGenotypeHumansMaleMarkov ChainsMonte Carlo MethodPhenotype

Identifiers

PMID23149458
PMCPMC3668646

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.