ArticleThe Science of the total environment2013
The Near-Road Exposures and Effects of Urban Air Pollutants Study (NEXUS): study design and methods.
Article in The Science of the total environment, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 81 citations in OpenAlex.
- Comparative analysis of ambient, in-home, and personal exposures reveals associations between breathing zone pollutant levels and asthma exacerbations in high-risk children.Respiratory research · 2025Article
- High-Precision Microscale Particulate Matter Prediction in Diverse Environments Using a Long Short-Term Memory Neural Network and Street View Imagery.Environmental science & technology · 2024Article
- Factors Influencing Classroom Exposures to Fine Particles, Black Carbon, and Nitrogen Dioxide in Inner-City Schools and Their Implications for Indoor Air Quality.Environmental health perspectives · 2022Article
- Mobile monitoring and spatial prediction of black carbon in Cairo, Egypt.Environmental monitoring and assessment · 2021Article
- Impact of School Location on Children's Air Pollution Exposure.Journal of urban affairs · 2020Article
- Enhancing Models and Measurements of Traffic-Related Air Pollutants for Health Studies Using Dispersion Modeling and Bayesian Data Fusion.Research report (Health Effects Institute) · 2020Article
- A meta-analysis of selected near-road air pollutants based on concentration decay rates.Heliyon · 2019Article
- Indoor air quality in inner-city schools and its associations with building characteristics and environmental factors.Environmental research · 2019Article
- Influence of viral infection on the relationships between airway cytokines and lung function in asthmatic children.Respiratory research · 2018Article
- Sensitivity analysis of the near-road dispersion model RLINE - an evaluation at Detroit, Michigan.Atmospheric environment (Oxford, England : 1994) · 2018Article
- On-Road Chemical Transformation as an Important Mechanism of NOEnvironmental science & technology · 2018Article
- Development and Evaluation of the R-LINE Model Algorithms to Account for Chemical Transformation in the Near-road Environment.Transportation research. Part D, Transport and environment · 2018Article
- Evaluation of Traffic Density Parameters as an Indicator of Vehicle Emission-Related Near-Road Air Pollution: A Case Study with NEXUS Measurement Data on Black Carbon.International journal of environmental research and public health · 2017Article
- Finely Resolved On-Road PMRisk analysis : an official publication of the Society for Risk Analysis · 2017Article
- Combustion-Related Organic Species in Temporally Resolved Urban Airborne Particulate Matter.Air quality, atmosphere, & health · 2017Article
- Community-based participatory research for the study of air pollution: a review of motivations, approaches, and outcomes.Environmental monitoring and assessment · 2017Review
- Use of Medicaid and housing data may help target areas of high asthma prevalence.The Journal of asthma : official journal of the Association for the Care of Asthma · 2017Article
- Outdoor Environment and Pediatric Asthma: An Update on the Evidence from North America.Canadian respiratory journal · 2017Review
- Near-Road Exposure and Impact of Air Pollution on Allergic Diseases in Elementary School Children: A Cross-Sectional Study.Yonsei medical journal · 2016Article
- Comparison of Highly Resolved Model-Based Exposure Metrics for Traffic-Related Air Pollutants to Support Environmental Health Studies.International journal of environmental research and public health · 2015Article
Corrections and comments
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Authors and funding
16 authors at 2 institutions in 1 country.
Funding
Abstract
The Near-Road Exposures and Effects of Urban Air Pollutants Study (NEXUS) was designed to examine the relationship between near-roadway exposures to air pollutants and respiratory outcomes in a cohort of asthmatic children who live close to major roadways in Detroit, Michigan USA. From September 2010 to December 2012 a total of 139 children with asthma, ages 6-14, were enrolled in the study on the basis of the proximity of their home to major roadways that carried different amounts of diesel traffic. The goal of the study was to investigate the effects of traffic-associated exposures on adverse respiratory outcomes, biomolecular markers of inflammatory and oxidative stress, and how these exposures affect the frequency and severity of respiratory viral infections in a cohort of children with asthma. An integrated measurement and modeling approach was used to quantitatively estimate the contribution of traffic sources to near-roadway air pollution and evaluate predictive models for assessing the impact of near-roadway pollution on children's exposures. Two intensive field campaigns were conducted in Fall 2010 and Spring 2011 to measure a suite of air pollutants including PM2.5 mass and composition, oxides of nitrogen (NO and NO2), carbon monoxide, and black carbon indoors and outdoors of 25 participants' homes, at two area schools, and along a spatial transect adjacent to I-96, a major highway in Detroit. These data were used to evaluate and refine models to estimate air quality and exposures for each child on a daily basis for the health analyses. The study design and methods are described, and selected measurement results from the Fall 2010 field intensive are presented to illustrate the design and successful implementation of the study. These data provide evidence of roadway impacts and exposure variability between study participants that will be further explored for associations with the health measures.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.