ArticleThe Journal of physiology2013
Evolutionarily conserved differences in pallial and thalamic short-term synaptic plasticity in striatum.
Article in The Journal of physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 32 citations in OpenAlex.
- Olfactory Projections to Locomotor Control Centers in the Sea Lamprey.International journal of molecular sciences · 2024Article
- The Basal Ganglia Downstream Control of Action - An Evolutionarily Conserved Strategy.Current neuropharmacology · 2024Review
- The neural bases of vertebrate motor behaviour through the lens of evolution.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- The Dopaminergic Control of Movement-Evolutionary Considerations.International journal of molecular sciences · 2021Review
- Differential expression of somatostatin genes in the central nervous system of the sea lamprey.Brain structure & function · 2021Article
- Article
- Tectal microcircuit generating visual selection commands on gaze-controlling neurons.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Ontogenetic shifts in brain scaling reflect behavioral changes in the life cycle of the pouched lamprey Geotria australis.Frontiers in neuroscience · 2015Article
- GABAergic and glycinergic inputs modulate rhythmogenic mechanisms in the lamprey respiratory network.The Journal of physiology · 2014Article
- The evolutionary origin of the vertebrate basal ganglia and its role in action selection.The Journal of physiology · 2013Article
- Independent circuits in the basal ganglia for the evaluation and selection of actions.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Forebrain dopamine neurons project down to a brainstem region controlling locomotion.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Neuronal mechanisms of respiratory pattern generation are evolutionary conserved.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Dopamine differentially modulates the excitability of striatal neurons of the direct and indirect pathways in lamprey.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The striatum of the basal ganglia is conserved throughout the vertebrate phylum. Tracing studies in lamprey have shown that its afferent inputs are organized in a manner similar to that of mammals. The main inputs arise from the thalamus (Th) and lateral pallium (LPal; the homologue of cortex) that represents the two principal excitatory glutamatergic inputs in mammals. The aim here was to characterize the pharmacology and synaptic dynamics of afferent fibres from the LPal and Th onto identified striatal neurons to understand the processing taking place in the lamprey striatum. We used whole-cell current-clamp recordings in acute slices of striatum with preserved fibres from the Th and LPal, as well as tract tracing and immunohistochemistry. We show that the Th and LPal produce monosynaptic excitatory glutamatergic input through NMDA and AMPA receptors. The synaptic input from the LPal displayed short-term facilitation, unlike the Th input that instead displayed strong short-term synaptic depression. There was also an activity-dependent recruitment of intrastriatal oligosynaptic inhibition from both inputs. These results indicate that the two principal inputs undergo different activity-dependent short-term synaptic plasticity in the lamprey striatum. The difference observed between Th and LPal (cortical) input is also observed in mammals, suggesting a conserved trait throughout vertebrate evolution.
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