ArticlePloS one2012
The spectrum of cancers in West Africa: associations with human immunodeficiency virus.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- Noncommunicable diseases among HIV-infected persons in low-income and middle-income countries: a systematic review and meta-analysis.AIDS (London, England) · 2018Pooled it
- Immunogenicity and safety of the human papillomavirus 6, 11, 16, 18 vaccine in HIV-infected young women.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2013Trial
- Prevalence and factors associated with high-risk human papillomavirus infection and cervical lesions among women with HIV in Addis Ababa, Ethiopia.BMC cancer · 2025Article
- Cervical cancer screening uptake in Côte d'Ivoire: Analysis of prevalence and associated factors.BMC public health · 2025Article
- Cancer in People with HIV.Infectious disease clinics of North America · 2024Review
- Barriers to early diagnosis of cervical cancer: a mixed-method study in Côte d'Ivoire, West Africa.BMC women's health · 2023Article
- Hepatitis B Virus Research in South Africa.Viruses · 2022Review
- Hepatocellular carcinoma in Hepatitis B and Human Immunodeficiency Virus coinfection in Africa: a focus on surveillance.Hepatoma research · 2022Article
- Current impact of viral hepatitis on liver cancer development: The challenge remains.World journal of gastroenterology · 2021Review
- Human papillomavirus-based cervical precancer screening with visual inspection with acetic acid triage to achieve same-day treatments among women living with human immunodeficiency virus infection: test-of-concept study in Ibadan, Nigeria.The Pan African medical journal · 2021Article
- Hepatitis B virus-associated hepatocellular carcinoma in South Africa in the era of HIV.BMC gastroenterology · 2020Article
- Cervical Cancer Screening Uptake and Associated Factors among HIV-Positive Women in Ethiopia: A Systematic Review and Meta-Analysis.Advances in preventive medicine · 2020Article
- INVASIVE CERVICAL CANCER IN IBADAN: SOCIO-SEXUAL CHARACTERISTICS, CLINICAL STAGE AT PRESENTATION, HISTOPATHOLOGY DISTRIBUTIONS AND HIV STATUS.African journal of infectious diseases · 2019Article
- Etiology of hepatocellular carcinoma in West Africa, a case-control study.International journal of cancer · 2018Article
- Evolving epidemiology of HIV-associated malignancies.Current opinion in HIV and AIDS · 2017Review
- Comprehensive knowledge and uptake of cervical cancer screening is low among women living with HIV/AIDS in Northwest Ethiopia.Gynecologic oncology research and practice · 2017Article
- Mapping the Epidemiology of Kaposi Sarcoma and Non-Hodgkin Lymphoma Among Children in Sub-Saharan Africa: A Review.Pediatric blood & cancer · 2016Review
- Cancer and HIV infection in referral hospitals from four West African countries.Cancer epidemiology · 2015Article
- Cancer in the HIV-Infected Host: Epidemiology and Pathogenesis in the Antiretroviral Era.Current HIV/AIDS reports · 2015Review
- Human papillomavirus in the HIV-infected host: epidemiology and pathogenesis in the antiretroviral era.Current HIV/AIDS reports · 2015Review
Corrections and comments
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Authors and funding
13 authors at 5 institutions in 3 countries.
Funding
Abstract
backgroundCancer is a growing co-morbidity among HIV-infected patients worldwide. With the scale-up of antiretroviral therapy (ART) in developing countries, cancer will contribute more and more to the HIV/AIDS disease burden. Our objective was to estimate the association between HIV infection and selected types of cancers among patients hospitalized for diagnosis or treatment of cancer in West Africa.
methodsA case-referent study was conducted in referral hospitals in Côte d'Ivoire and Benin. Each participating clinical ward enrolled all adult patients seeking care for a confirmed diagnosis of cancer and clinicians systematically proposed an HIV test. HIV prevalence was compared between AIDS-defining cancers and a subset of selected non-AIDS defining cancers to a referent group of non-AIDS defining cancers not reported in the literature to be positively or inversely associated with HIV. An unconditional logistic model was used to estimate odds ratios (OR) and their 95% confidence intervals (CI) of the risk of being HIV-infected for selected cancers sites compared to a referent group of other cancers.
resultsThe HIV overall prevalence was 12.3% (CI 10.3-14.4) among the 1,017 cancer cases included. A total of 442 patients constituted the referent group with an HIV prevalence of 4.7% (CI 2.8-6.7). In multivariate analysis, Kaposi sarcoma (OR 62.2 [CI 22.1-175.5]), non-Hodgkin lymphoma (4.0 [CI 2.0-8.0]), cervical cancer (OR 7.9 [CI 3.8-16.7]), anogenital cancer (OR 11.6 [CI 2.9-46.3]) and liver cancer (OR 2.7 [CI 1.1-7.7]) were all associated with HIV infection.
conclusionsIn a time of expanding access to ART, AIDS-defining cancers remain highly associated with HIV infection. This is to our knowledge, the first study reporting a significant association between HIV infection and liver cancer in sub-Saharan Africa.
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Registered trials
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