ArticleNature photonics2011
Molecular imaging true-colour spectroscopic optical coherence tomography.
Article in Nature photonics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
103 citing papers in PubMed, 1 synthesis or guideline pooled it, 212 citations in OpenAlex.
- Optical biopsy of epithelial cancers by optical coherence tomography (OCT).Lasers in medical science · 2014Pooled it
- From intravascular imaging to adaptive vascular care: intelligent photonics and digital twins in panvascular disease.Light, science & applications · 2026Review
- Visible Light Optical Coherence Tomography Reveals Aging at the Retinal Pigment Epithelium-Bruch's Membrane Interface.bioRxiv : the preprint server for biology · 2026Article
- Automated lipid detection in spectroscopic optical coherence tomography using a weakly supervised deep learning network.Biomedical optics express · 2026Article
- Scattering Coefficient Estimation Using Thin-Film Phantoms with a Spectral-Domain Dental OCT System.Sensors (Basel, Switzerland) · 2026Article
- Proof-of-Concept Study: Hyperspectral Imaging for Quantification of DKK-3 Expression in Oropharyngeal Carcinoma.Bioengineering (Basel, Switzerland) · 2025Article
- Article
- Magnetically Controlled Reversible Photomagnetic Nanoactuators for Dynamic Contrast Enhancement in Optical Coherence Tomography.Advanced materials (Deerfield Beach, Fla.) · 2025Article
- Visible Light Optical Coherence Tomography: Technology and Biomedical Applications.Bioengineering (Basel, Switzerland) · 2025Review
- Visible light optical coherence tomography for assessing retinal structure and function in diseased mouse models.Biomedical optics express · 2025Article
- Visible-light optical coherence tomography and its applications.Neurophotonics · 2025Review
- Multimodal optoacoustic imaging: methods and contrast materials.Chemical Society reviews · 2024Review
- Technology Selection for Inline Topography Measurement with Rover-Borne Laser Spectrometers.Sensors (Basel, Switzerland) · 2024Article
- Skin cancer margin detection using nanosensitive optical coherence tomography and a comparative study with confocal microscopy.Biomedical optics express · 2022Article
- Multiple forward scattering reduces the measured scattering coefficient of whole blood in visible-light optical coherence tomography.Biomedical optics express · 2022Article
- Molecular Contrast Optical Coherence Tomography and Its Applications in Medicine.International journal of molecular sciences · 2022Review
- Portable, handheld, and affordable blood perfusion imager for screening of subsurface cancer in resource-limited settings.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- A Baseline Study of Oxygen Saturation in Parafoveal Vessels Using Visible Light Optical Coherence Tomography.Frontiers in medicine · 2022Article
- Accessing depth-resolved high spatial frequency content from the optical coherence tomography signal.Scientific reports · 2021Article
- A review of low-cost and portable optical coherence tomography.Progress in biomedical engineering (Bristol, England) · 2021Article
43 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Molecular imaging holds a pivotal role in medicine due to its ability to provide invaluable insight into disease mechanisms at molecular and cellular levels. To this end, various techniques have been developed for molecular imaging, each with its own advantages and disadvantages(1-4). For example, fluorescence imaging achieves micrometre-scale resolution, but has low penetration depths and is mostly limited to exogenous agents. Here, we demonstrate molecular imaging of endogenous and exogenous chromophores using a novel form of spectroscopic optical coherence tomography. Our approach consists of using a wide spectral bandwidth laser source centred in the visible spectrum, thereby allowing facile assessment of haemoglobin oxygen levels, providing contrast from readily available absorbers, and enabling true-colour representation of samples. This approach provides high spectral fidelity while imaging at the micrometre scale in three dimensions. Molecular imaging true-colour spectroscopic optical coherence tomography (METRiCS OCT) has significant implications for many biomedical applications including ophthalmology, early cancer detection, and understanding fundamental disease mechanisms such as hypoxia and angiogenesis.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.