ReviewApplied and environmental microbiology2013
Taking the starch out of oral biofilm formation: molecular basis and functional significance of salivary α-amylase binding to oral streptococci.
Review in Applied and environmental microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 68 citations in OpenAlex.
- Amylase Binding to Oral Streptococci: A Key Interaction for Human Oral Microbial Ecology, Adaptation and Fitness.Biomolecules · 2025Review
- The role of AMY1 gene copy number variation in dental caries susceptibility: insights from a Turkish population.BMC oral health · 2025Article
- Salivary analysis in adults with and without root caries in South coastal population of India - A cross-sectional analytical study.Journal of conservative dentistry and endodontics · 2025Article
- Positive Role of Saliva in the Oral Microbiome.Advances in experimental medicine and biology · 2025Review
- Microparticles from dental calculus disclose paleoenvironmental and palaeoecological records.Ecology and evolution · 2024Article
- Influence of Swimming Training Session on Selected Saliva Components in Youth Swimmers.Frontiers in physiology · 2022Article
- Surface Effect of Nano-Roughened Yttria-Doped Zirconia on Salivary Protein Adhesion.Materials (Basel, Switzerland) · 2021Article
- Polymicrobial communities in periodontal disease: Their quasi-organismal nature and dialogue with the host.Periodontology 2000 · 2021Review
- The evolution and changing ecology of the African hominid oral microbiome.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Combined effect of starch and sucrose on carbonic anhydrase VI activity in saliva and biofilm of children with early childhood caries. Exposure to starch and sucrose alters carbonic anhydrase VI activity in saliva and biofilm.Clinical oral investigations · 2021Article
- The role of mechanical control of biofilm in the salivary pH after sucrose exposure in children with early childhood caries.Scientific reports · 2021Article
- Effects of altitude on human oral microbes.AMB Express · 2021Article
- Murine Salivary Amylase Protects AgainstFrontiers in physiology · 2021Article
- Amylases: Biofilm Inducer or Biofilm Inhibitor?Frontiers in cellular and infection microbiology · 2021Review
- Proteome difference among the salivary proteins adsorbed onto metallic orthodontic brackets and hydroxyapatite discs.PloS one · 2021Article
- Article
- Cloning, Expression and Characterization of a Novel α-Amylase from Salinispora arenicola CNP193.The protein journal · 2019Article
- Article
- Genetics ofMicrobiology spectrum · 2019Article
- Oral Biofilms: Pathogens, Matrix, and Polymicrobial Interactions in Microenvironments.Trends in microbiology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
α-Amylase-binding streptococci (ABS) are a heterogeneous group of commensal oral bacterial species that comprise a significant proportion of dental plaque microfloras. Salivary α-amylase, one of the most abundant proteins in human saliva, binds to the surface of these bacteria via specific surface-exposed α-amylase-binding proteins. The functional significance of α-amylase-binding proteins in oral colonization by streptococci is important for understanding how salivary components influence oral biofilm formation by these important dental plaque species. This review summarizes the results of an extensive series of studies that have sought to define the molecular basis for α-amylase binding to the surface of the bacterium as well as the biological significance of this phenomenon in dental plaque biofilm formation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.