ArticleHuman vaccines & immunotherapeutics2013
Assessing the burden of HPV-related cancers in Appalachia.
Article in Human vaccines & immunotherapeutics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 34 citations in OpenAlex.
- A Mail-Based HPV Self-Collection Program to Increase Cervical Cancer Screening in Appalachia: Results of a Group Randomized Trial.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025Trial
- Results of a Multilevel Intervention Trial to Increase Human Papillomavirus (HPV) Vaccine Uptake among Adolescent Girls.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2016Trial
- Disparities in Human Papillomavirus-Associated Cancer Incidence by Appalachian Residence.JAMA network open · 2025Article
- Head and Neck Cancer Mortality in the Appalachian Region.JAMA otolaryngology-- head & neck surgery · 2025Article
- Serum profiling of the antibody response to HPV in women with or without abnormal cervical cytology undergoing cervical cancer screening.Frontiers in immunology · 2025Article
- Results of a Human Papillomavirus Self-Collection Educational Intervention for Health Care Providers in Appalachia.Women's health reports (New Rochelle, N.Y.) · 2025Article
- Temporal increase in the incidence of anal squamous cell carcinoma in Kentucky and factors associated with adverse outcomes.Cancer medicine · 2023Article
- Geographical disparities in human papillomavirus herd protection.Cancer medicine · 2020Article
- HPV Vaccine Coverage among Adolescent Males in Ohio: Results of a Longitudinal Study.Ohio journal of public health · 2019Article
- Assessing Knowledge Sharing in Cancer Screening Among High-, Middle-, and Low-Income Countries: Insights From the International Cancer Screening Network.Journal of global oncology · 2019Article
- Results of a Pilot Study of a Mail-Based Human Papillomavirus Self-Testing Program for Underscreened Women From Appalachian Ohio.Sexually transmitted diseases · 2019Article
- Cancer-Related Beliefs and Perceptions in Appalachia: Findings from 3 States.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2019Article
- Community-Academic Partnerships: Approaches to Engagement.American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting · 2019Review
- Effects of an Education Intervention about HPV Self-Testing for Healthcare Providers and Staff.Journal of cancer education : the official journal of the American Association for Cancer Education · 2018Article
- Disparity in rates of HPV infection and cervical cancer in underserved US populations.Frontiers in bioscience (Scholar edition) · 2017Review
- Need for addressing oral health disparities in rural Appalachia.Health promotion perspectives · 2017Article
- A Community-Academic Partnership to Increase Pap Testing in Appalachian Kentucky.American journal of preventive medicine · 2015Article
- The process of engaging members from two underserved populations in the development of interventions to promote the uptake of the HPV vaccine.Health promotion practice · 2015Article
- Fatalistic beliefs and completion of the HPV vaccination series among a sample of young Appalachian Kentucky women.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2015Article
- Acceptability of HPV vaccine for males and preferences for future education programs among Appalachian residents.American journal of men's health · 2014Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 1 country.
Funding
Abstract
Appalachia is a geographic region with existing cancer disparities, yet little is known about its burden of HPV-related cancers outside of cervical cancer. We assessed the burden of HPV-related cancers in three Appalachian states and made comparisons to non-Appalachian regions. We examined 1996-2008 cancer registry data for Ohio, Kentucky, West Virginia and the Surveillance, Epidemiology and End Results (SEER) 9 program. For each gender, we calculated age-adjusted incidence rates per 100,000 population for each HPV-related cancer type (cervical, vaginal, vulvar, penile, anal and oral cavity and pharyngeal cancers) and all HPV-related cancers combined. Incidence rates among females for all HPV-related cancers combined were higher in Appalachian Kentucky [24.6 (95% CI: 23.5-25.7)], West Virginia [22.8 (95% CI: 22.0-23.6)] and Appalachian Ohio [21.9 (95% CI: 21.0-22.8)] than SEER 9 [18.8 (95% CI: 18.6-19.0)]. Similar disparities were found among females when examining cervical and vulvar cancers separately. Among males, Appalachian [21.3 (95% CI: 20.2-22.4)] and non-Appalachian [21.9 (95% CI: 21.2-22.7)] Kentucky had higher incidence rates for all HPV-related cancers combined than SEER 9 [18.3 (95% CI: 18.1-18.6)]. The incidence rate of all HPV-related cancers combined was higher among males from Appalachian Ohio compared with those from non-Appalachian Ohio [17.6 (95% CI: 16.8-18.5) vs. 16.3 (95% CI: 16.0-16.6)]. Our study suggests that HPV-related cancer disparities exist in Appalachia beyond the known high cervical cancer incidence rates. These results have important public health implications by beginning to demonstrate the potential impact that widespread HPV vaccination could have in Appalachia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.