Trial reportInfection control and hospital epidemiology2012
Effective antimicrobial stewardship in a long-term care facility through an infectious disease consultation service: keeping a LID on antibiotic use.
Trial report in Infection control and hospital epidemiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 9 syntheses or guidelines pooled it, 134 citations in OpenAlex.
- Impact of interprofessional collaboration between long-term care physicians and medical specialists on quality of care and quality of life of long-term care facility residents: a systematic review.European geriatric medicine · 2026Pooled it
- How do aged-care staff feel about antimicrobial stewardship? A systematic review of staff attitudes in long-term residential aged-care.Antimicrobial resistance and infection control · 2022Pooled it
- Pooled it
- Effectiveness of interventions targeting antibiotic use in long-term aged care facilities: a systematic review and meta-analysis.BMJ open · 2020Pooled it
- Antimicrobial Stewardship Programs in Long-Term Care Settings: A Meta-Analysis and Systematic Review.Journal of the American Geriatrics Society · 2019Pooled it
- Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA).Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Guideline
- Interventions to improve antibiotic prescribing practices for hospital inpatients.The Cochrane database of systematic reviews · 2017Pooled it
- Implementing an Antibiotic Stewardship Program: Guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2016Guideline
- Asymptomatic carriers of toxigenic C. difficile in long-term care facilities: a meta-analysis of prevalence and risk factors.PloS one · 2015Pooled it
- Cluster-Randomized Controlled Trial of Enhanced Carbapenem-Resistant Enterobacterales Prevention Program in General Medicine Wards, Siriraj Hospital.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026Trial
- Syndromic Antibiograms and Nursing Home Clinicians' Antibiotic Choices for Urinary Tract Infections.JAMA network open · 2023Trial
- Physicians' understanding of antibiotic prescribing in Korean long-term care hospitals: a multicenter cross-sectional study.Journal of health, population, and nutrition · 2026Article
- Experience in Implementing Colonization Screening in a Multidisciplinary County Clinical Hospital in Romania.Microorganisms · 2025Article
- Understanding and mapping the antibiotic prescribing and administration process in assisted living facilities.Exploratory research in clinical and social pharmacy · 2025Article
- Using behavioural science to improve antibiotic stewardship in Canadian long-term care homes: Protocol for a multi-center cluster randomized quality improvement study.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2025Article
- Barriers to the implementation of antimicrobial stewardship programmes in long-term care facilities: a scoping review.The Journal of antimicrobial chemotherapy · 2024Article
- Development of a risk prediction model for subsequent infection after colonization with carbapenem-resistant Enterobacterales: a retrospective cohort study.Antimicrobial resistance and infection control · 2024Article
- Antibiotic postprescribing modification opportunities among nursing home residents treated for urinary tract infection.Infection control and hospital epidemiology · 2023Article
- The role of infectious disease consultations in the management of patients with fever in a long-term care facility.PloS one · 2023Article
- Antibiotic prescribing and antimicrobial stewardship in long-term care facilities: Past interventions and implementation challenges.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2022Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 5 institutions in 1 country.
Funding
Abstract
designWe introduced a long-term care facility (LTCF) infectious disease (ID) consultation service (LID service) that provides on-site consultations to residents of a Veterans Affairs (VA) LTCF. We determined the impact of the LID service on antimicrobial use and Clostridium difficile infections at the LTCF.
settingA 160-bed VA LTCF.
methodsSystemic antimicrobial use and positive C. difficile tests at the LTCF were compared for the 36 months before and the 18 months after the initiation of the ID consultation service through segmented regression analysis of an interrupted time series.
resultsRelative to that in the preintervention period, total systemic antibiotic administration decreased by 30% (P<.001), with significant reductions in both oral (32%; P<.001) and intravenous (25%; P=.008) agents. The greatest reductions were seen for tetracyclines (64%; P<.001), clindamycin (61%; P<.001), sulfamethoxazole/trimethoprim (38%; P<.001), fluoroquinolones (38%; P<.001), and β-lactam/β-lactamase inhibitor combinations (28%; P<.001). The rate of positive C. difficile tests at the LTCF declined in the postintervention period relative to preintervention rates (P=.04).
conclusionsImplementation of an LTCF ID service led to a significant reduction in total antimicrobial use. Bringing providers with ID expertise to the LTCF represents a new and effective means to achieve antimicrobial stewardship.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.