Evidence map›Paper›PMID 23143169›Full record

ArticleSurgery today2013

Efficacy of PET-CT for predicting the malignant potential of gastrointestinal stromal tumors.

Kozo Yoshikawa, Mitsuo Shimada, Nobuhiro Kurita, Hirohiko Sato, Takashi Iwata, Shinya Morimoto, Tomohiko Miyatani, Hideya Kashihara, Chie Takasu, Noriko Matsumoto

Abstract read
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In one paragraph

Article in Surgery today, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Cancers · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Value ofJournal of gastrointestinal oncology · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. The Impact of Imatinib on Survival and Treatment Trends for Small Bowel and Colorectal Gastrointestinal Stromal Tumors.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020
    Article
  12. Review
  13. Article
  14. Prognostic value of fluorineJournal of veterinary internal medicine · 2019
    Article
  15. Article
  16. How best to manage gastrointestinal stromal tumor.World journal of clinical oncology · 2017
    Review
  17. Article
  18. Article
  19. Gastrointestinal autonomic nerve tumors: a clinical review.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2015
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Kozo YoshikawaThe Department of Surgery, The University of Tokushima, 3-18-15 Kuramoto-cho, Tokushima, 770-8503, Japan.
Mitsuo Shimada
Nobuhiro Kurita
Hirohiko Sato
Takashi Iwata
Shinya Morimoto
Tomohiko Miyatani
Hideya Kashihara
Chie Takasu
Noriko Matsumoto
Tokushima University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposesGastrointestinal stromal tumor (GIST) is the most common sarcoma of the intestinal tract. The risk category is usually determined by tumor size and mitotic count, but accurate preoperative diagnosis of GIST is very difficult. The purpose of this study is to evaluate the efficacy of positron emission tomography (PET)-CT for predicting the malignant potential of gastrointestinal stromal tumors.

methodsTen patients with GIST who underwent a preoperative PET-CT examination were divided into two groups by risk category, and various factors were compared between the two groups. The relationships between the maximum standardized uptake value (SUVmax) and GIST parameters were examined.

resultsPatients were classified into two groups by their risk category: (low/intermediate-risk or high-risk). The SUVmax was significantly higher in the high-risk group (11.0 ± 3.04) than in the low/intermediate-risk group (2.1 ± 1.5). The Ki67 labeling index was also significantly higher in the high-risk group (8.63 ± 6.2) than in the low/intermediate-risk group (1.75 ± 0.52). There was a significant correlation between the Ki67 labeling index and the SUVmax (p = 0.028) and between the mitotic index and the SUVmax (p = 0.029).

conclusionsPET-CT can predict malignant potential. Cases with a SUVmax of over 5 may have malignant potential.

Indexed as

AdultAgedFemaleFluorine RadioisotopesFluorodeoxyglucose F18Gastrointestinal NeoplasmsGastrointestinal Stromal TumorsHumansMaleMiddle AgedNeoplasm StagingPositron-Emission TomographyRadiopharmaceuticalsRiskTomography, X-Ray ComputedFluorine RadioisotopesFluorodeoxyglucose F18Radiopharmaceuticals

Identifiers

PMID23143169
OpenAlexW1988083613

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.