ArticleJournal of comparative physiology. B, Biochemical, systemic, and environmental physiology2013
Differential expression of Na+, K(+)-ATPase α-1 isoforms during seawater acclimation in the amphidromous galaxiid fish Galaxias maculatus.
Article in Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 49 citations in OpenAlex.
- Ecophysiological variance within fish populations occupying different trophic niches of contrasting ecoregions.Fish physiology and biochemistry · 2025Article
- Paralog switching facilitates diadromy: ontogenetic, microevolutionary and macroevolutionary evidence.Oecologia · 2024Article
- Effects of Dietary Inosine 5'-Monophosphate Supplementation on the Growth Performance and Salinity and Oxidative Stress Resistance of Gibel Carp (Antioxidants (Basel, Switzerland) · 2024Article
- The role of salinity in recovery of white sturgeon (Conservation physiology · 2023Article
- Behavioural and physiological responses to salinization and air exposure during the ontogeny of a freshwater South American snail.Conservation physiology · 2023Article
- Melatonin integrates multidimensional regulation of NaFrontiers in physiology · 2022Article
- The time course of molecular acclimation to seawater in a euryhaline fish.Scientific reports · 2021Article
- Homeoviscous adaptation occurs with thermal acclimation in biological membranes from heart and gill, but not the brain, in the Antarctic fish Notothenia coriiceps.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2021Article
- Pseudobranch mimics gill in expressing NaFish physiology and biochemistry · 2020Article
- NaProceedings. Biological sciences · 2019Article
- The effects of acute transfer to freshwater on ion transporters of the pharyngeal cavity in European seabass (Dicentrarchus labrax).Fish physiology and biochemistry · 2018Article
- Molecular characterization and expression of NaFish physiology and biochemistry · 2016Article
- Sublethal salinity stress contributes to habitat limitation in an endangered estuarine fish.Evolutionary applications · 2016Article
- Does Japanese medaka (Oryzias latipes) exhibit a gill Na(+)/K(+)-ATPase isoform switch during salinity change?Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2016Article
- Short-term Effects of Hypertonic Shock on NaZoological studies · 2016Article
- Isolation Driven Divergence in Osmoregulation in Galaxias maculatus (Jenyns, 1848) (Actinopterygii: Osmeriformes).PloS one · 2016Article
- Comparisons of two types of teleostean pseudobranchs, silver moony (Monodactylus argenteus) and tilapia (Oreochromis mossambicus), with salinity-dependent morphology and ion transporter expression.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2015Article
- Acclimation of brackish water pearl spot (Etroplus suratensis) to various salinities: relative changes in abundance of branchial Na(+)/K (+)-ATPase and Na (+)/K (+)/2Cl (-) co-transporter in relation to osmoregulatory parameters.Fish physiology and biochemistry · 2014Article
- The skin of fish as a transport epithelium: a review.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2013Review
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inanga (Galaxias maculatus) is an amphidromous fish with a well-known capacity to withstand a wide range of environmental salinities. To investigate the molecular mechanisms facilitating acclimation of inanga to seawater, several isoforms of the Na(+), K(+)-ATPase ion transporter were identified. This included three α-1 (a, b and c), an α-2 and two α-3 (a and b) isoforms. Phylogenetic analysis showed that the inanga α-1a and α-1b formed a clade with the α-1a and α-1b isoforms of rainbow trout, while another clade contained the α-1c isoforms of these species. The expression of all the α-1 isoforms was modulated after seawater exposure (28‰). In gills, the expression of the α-1a isoform was progressively down-regulated after seawater exposure, while the expression of the α-1b isoform was up-regulated. The α-1c isoform behaved similarly to the α-1a, although changes were less dramatic. Physiological indicators of salinity acclimation matched the time frame of the changes observed at the molecular level. A 24-h osmotic shock period was highlighted by small increases in plasma osmolality, plasma Na(+) and a decrease in muscle tissue water content. Thereafter, these values returned close to their pre-exposure (freshwater) values. Na(+), K(+)-ATPase activity showed a decreasing trend over the first 72 h following seawater exposure, but activity increased after 240 h. Our results indicate that inanga is an excellent osmoregulator, an ability that is conferred by the rapid activation of physiological and molecular responses to salinity change.
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