ReviewCurrent drug targets2012
Medicinal properties of the Jamaican pepper plant Pimenta dioica and Allspice.
Review in Current drug targets, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 87 citations in OpenAlex.
- Anticonvulsant Potential and Network Pharmacology Analysis of Pimenta dioica (L.) Merr.Chemistry & biodiversity · 2026Article
- One Health as a potential platform to rescue the neglected fruit trees in Yucatan, Mexico.Science in One Health · 2024Review
- Eugenol-Rich Essential Oil fromPharmaceuticals (Basel, Switzerland) · 2023Article
- Spice-Derived Phenolic Compounds: Potential for Skin Cancer Prevention and Therapy.Molecules (Basel, Switzerland) · 2023Review
- Assessment of Antioxidant Stability of Meat Pâté withAntioxidants (Basel, Switzerland) · 2023Article
- Natural essential oil mix of sweet orange peel, cumin, and allspice elicits anti-inflammatory activity and pharmacological safety similar to non-steroidal anti-inflammatory drugs.Saudi journal of biological sciences · 2022Article
- Medicinal plants cultivated in urban home gardens in Heredia, Costa Rica.Journal of ethnobiology and ethnomedicine · 2022Article
- Dual Inhibitory Activity of Petroselinic Acid Enriched in Fennel AgainstFrontiers in microbiology · 2022Article
- Chemical Composition, Insecticidal and Mosquito Larvicidal Activities of Allspice (Molecules (Basel, Switzerland) · 2021Article
- Article
- GT198 Is a Target of Oncology Drugs and Anticancer Herbs.Frontiers in oral health · 2021Article
- Peppers: A "Hot" Natural Source for Antitumor Compounds.Molecules (Basel, Switzerland) · 2021Review
- Traditional Herbal Medicine in Mesoamerica: Toward Its Evidence Base for Improving Universal Health Coverage.Frontiers in pharmacology · 2020Review
- Antimicrobial, Cytotoxic, and Anti-Inflammatory Activities ofBioMed research international · 2019Article
- Isolation and identification of three new chromones from the leaves of Pimenta dioica with cytotoxic, oestrogenic and anti-oestrogenic effects.Pharmaceutical biology · 2018Article
- The inhibitory potential ofFood science & nutrition · 2018Article
- Menopause in Latin America: Symptoms, attitudes, treatments and future directions in Costa Rica.Maturitas · 2017Review
- Allspice and Clove As Source of Triterpene Acids Activating the G Protein-Coupled Bile Acid Receptor TGR5.Frontiers in pharmacology · 2017Article
- Chemical Composition and Hypotensive Effect ofEvidence-based complementary and alternative medicine : eCAM · 2017Article
- Chemoprevention in gastrointestinal physiology and disease. Targeting the progression of cancer with natural products: a focus on gastrointestinal cancer.American journal of physiology. Gastrointestinal and liver physiology · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The Caribbean tropical tree, Pimenta dioica has been used for a variety of human endeavors, such as in perfumery industry, food spice, as a natural pesticide, and in folk medicine. Discovered in Jamaica during the voyages of Christopher Columbus, the dried unripe berries of P. dioica also known as Allspice can be found in all continents with unique names in over 50 languages. Systematic investigation of aromatic constituents of Pimenta leaves and its unripe berries, Allspice, have resulted in discovery of many and novel aromatic compounds, mostly glycosides and polyphenols that show antibacterial, hypotensive, anti-neuralgic and analgesic properties. Recent studies have shown two of the known compounds isolated from Allspice, Eugenol and Gallic acid have selective antiproliferative and anti-tumor properties on human cancer cells and their animal models. New characterization of novel compounds such as Ericifolin from the aqueous extract of Allspice berries show potent anti-prostate cancer and anti-breast cancer properties that can be verified in vitro as well as in vivo. Considering its purity, mostly available as "organically grown" berries, availability at low cost, wide acceptance in culinary delights of many cultures world-wide, Allspice may have an additional space in most households, in their medicine cabinets.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.