Trial reportPloS one2012
Muscle, skin and core temperature after -110°c cold air and 8°c water treatment.
Trial report in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Intramuscular Temperature Changes in the Quadriceps Femoris Muscle After Post-Exercise Cold-Water Immersion (10°C for 10 min): A Systematic Review With Meta-Analysis.Frontiers in sports and active living · 2021Pooled it
- Can Water Temperature and Immersion Time Influence the Effect of Cold Water Immersion on Muscle Soreness? A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2016Pooled it
- Whole-body cryotherapy (extreme cold air exposure) for preventing and treating muscle soreness after exercise in adults.The Cochrane database of systematic reviews · 2015Pooled it
- Effects of Immediate and Delayed Repeated Cold Exposure After Physical Exertion: A Randomized Controlled Trial.International journal of environmental research and public health · 2026Trial
- Effects of Whole-Body Cryotherapy Combined With Conventional Obesity Management Versus Obesity Management Alone: A Clinical Trial.Obesity (Silver Spring, Md.) · 2025Trial
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- Partial body cryotherapy exposure drives acute redistribution of circulating lymphocytes: preliminary findings.European journal of applied physiology · 2023Trial
- Acute Local Cooling to the Lower Body during Recovery Does Not Improve Repeated Vertical Jump Performance.International journal of environmental research and public health · 2021Trial
- Partial-body cryotherapy (-135°C) and cold-water immersion (10°C) after muscle damage in females.Scandinavian journal of medicine & science in sports · 2020Trial
- The physiological effects of daily cold-water immersion on 5-day tournament performance in international standard youth field-hockey players.European journal of applied physiology · 2020Trial
- Perfusion of the skin's microcirculation after cold-water immersion (10°C) and partial-body cryotherapy (-135°C).Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2019Trial
- Multiple Cold-Water Immersions Attenuate Muscle Damage but not Alter Systemic Inflammation and Muscle Function Recovery: A Parallel Randomized Controlled Trial.Scientific reports · 2018Trial
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- The effect of various cold-water immersion protocols on exercise-induced inflammatory response and functional recovery from high-intensity sprint exercise.European journal of applied physiology · 2014Trial
- Anthropometric characteristics and sex influence magnitude of skin cooling following exposure to whole body cryotherapy.BioMed research international · 2014Trial
- The effect of three different (-135°C) whole body cryotherapy exposure durations on elite rugby league players.PloS one · 2014Trial
- Thermal and cardiovascular responses to sauna are attenuated by adding cold water immersion to cooling breaks.Experimental physiology · 2026Article
- Short-Term Recovery Interventions Using Cryosauna, Cold-Water Immersion, and Foam Rolling in Mixed Martial Arts Athletes: A Polish Pilot Study.Sports (Basel, Switzerland) · 2026Article
- Isolated and Combined Effects of Cold, Heat and Hypoxia Therapies on Muscle Recovery Following Exercise-Induced Muscle Damage.Sports medicine (Auckland, N.Z.) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this investigation was to elucidate the reductions in muscle, skin and core temperature following exposure to -110°C whole body cryotherapy (WBC), and compare these to 8°C cold water immersion (CWI). Twenty active male subjects were randomly assigned to a 4-min exposure of WBC or CWI. A minimum of 7 days later subjects were exposed to the other treatment. Muscle temperature in the right vastus lateralis (n=10); thigh skin (average, maximum and minimum) and rectal temperature (n=10) were recorded before and 60 min after treatment. The greatest reduction (P<0.05) in muscle (mean ± SD; 1 cm: WBC, 1.6 ± 1.2°C; CWI, 2.0 ± 1.0°C; 2 cm: WBC, 1.2 ± 0.7°C; CWI, 1.7 ± 0.9°C; 3 cm: WBC, 1.6 ± 0.6°C; CWI, 1.7 ± 0.5°C) and rectal temperature (WBC, 0.3 ± 0.2°C; CWI, 0.4 ± 0.2°C) were observed 60 min after treatment. The largest reductions in average (WBC, 12.1 ± 1.0°C; CWI, 8.4 ± 0.7°C), minimum (WBC, 13.2 ± 1.4°C; CWI, 8.7 ± 0.7°C) and maximum (WBC, 8.8 ± 2.0°C; CWI, 7.2 ± 1.9°C) skin temperature occurred immediately after both CWI and WBC (P<0.05). Skin temperature was significantly lower (P<0.05) immediately after WBC compared to CWI. The present study demonstrates that a single WBC exposure decreases muscle and core temperature to a similar level of those experienced after CWI. Although both treatments significantly reduced skin temperature, WBC elicited a greater decrease compared to CWI. These data may provide information to clinicians and researchers attempting to optimise WBC and CWI protocols in a clinical or sporting setting.
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Registered trials
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