ArticleJournal of maxillofacial and oral surgery2010
Classifying odontogenic keratocysts as benign cystic neoplasms: a molecular insight into its aggressiveness.
Article in Journal of maxillofacial and oral surgery, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 13 citations in OpenAlex.
- Immunohistochemical Analysis of Dentigerous Cysts and Odontogenic Keratocysts Associated with Impacted Third Molars-A Systematic Review.Diagnostics (Basel, Switzerland) · 2024Review
- Aberrant immunoexpression of p53 tumour-suppressor and Bcl-2 family proteins (Bcl-2 and Bax) in ameloblastomas and odontogenic keratocysts.Journal of clinical and experimental dentistry · 2023Article
- Apoptosis and cell cycle aberrations in epithelial odontogenic lesions: An evidence by the expression of p53, Bcl-2 and Bax.Medicina oral, patologia oral y cirugia bucal · 2018Article
- P53 Protein Expression in Dental Follicle, Dentigerous Cyst, Odontogenic Keratocyst, and Inflammatory Subtypes of Cysts: An Immunohistochemical Study.Oman medical journal · 2017Article
- p53: Revealing the Unusual Suspect: a Study and Field Cancerization Minireview.Indian journal of surgical oncology · 2014Article
- Immunohistochemical Expression of PCNA in Epithelial Linings of Selected Odontogenic Lesions.Journal of clinical and diagnostic research : JCDR · 2013Article
- A molecular insight into the role of inflammation in the behavior and pathogenesis of odontogenic cysts.Annals of medical and health sciences research · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe present study was conducted with the aim to evaluate the expression of p53 in Odontogenic Keratocyst (OKC) and Ameloblastoma to correlate with the aggressiveness of these lesions. MATERIAL AND
methodsImmunohistochemical (IHC) staining was performed using anti-p53 antibody in eighteen cases each of OKC and ameloblastoma.
resultsp53 positivity was seen in all the cases of OKCs and ameloblastomas. p53 positive cells were seen predominantly in the suprabasal cell layer of OKC and in the peripheral pre-ameloblast like cells in ameloblastoma. Total p53 count was significantly higher in ameloblastoma as compared to OKC. But the intensely stained p53 cell count showed no statistically significant difference between the two lesions.
conclusionThe high p53 expression in OKC when compared with ameloblastoma, acknowledges OKC as an aggressive lesion and hence a more aggressive treatment modality is recommended.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.