Evidence map›Paper›PMID 23139487›Full record

ArticleJournal of maxillofacial and oral surgery2009

Morphological cell typing of osteoid clones derived from human bone marrow.

Olga Tsilenko, Vera Astachova, Vladislav Malanchuk, Francesco Carinci

Abstract read
In one paragraph

Article in Journal of maxillofacial and oral surgery, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Olga TsilenkoDept. of Oro-maxillofacial and Plastic Surgery, National Medical University, Kiev, Ukraine.
Vera Astachova
Vladislav Malanchuk
Francesco Carinci

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveBone Marrow Stem Cells (BMSC) are a 'reservoir' for bone regeneration. BMSC can be studied in vitro by cloning cells which are improperly named colonyforming units of fibroblasts (CFU-f). Thus we decided to study CFU-f organization and morphology to have (A) a parameter by which to compare normal and pathologic conditions and (B) to potentially select the most osteogenic clones.

methodsTwo hundred and forty bone samples were collected from 109 patients and primary cultures performed.

resultsAfter two weeks 9 cell types and 6 well organized types of colonies were detectable. Some have alkaline phosphatase (AP) activity.

conclusionThese data could be relevant to estimate the potential regeneration of bone.

Indexed as

Bone production in vitro systemCloneMorphologyStem cell

Identifiers

PMID23139487
PMCPMC3453941

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.