Evidence map›Paper›PMID 23139375›Full record

ArticleDiabetes care2013

Association between BMI measured within a year after diagnosis of type 2 diabetes and mortality.

Jennifer Logue, Jeremy J Walker, Graham Leese, Robert Lindsay, John McKnight, Andrew Morris, Sam Philip, Sarah Wild, Naveed Sattar, Scottish Diabetes Research Network Epidemiology Group

Abstract read
In one paragraph

Article in Diabetes care, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Association Between Trunk Fat Mass Index and Diabetes in a Multinational Population.Mayo Clinic proceedings. Innovations, quality & outcomes · 2025
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  7. Review
  8. Article
  9. Article
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  11. Article
  12. Article
  13. Article
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  15. Article
  16. Revisiting the Obesity Paradox in Health Care Expenditures Among Adults With Diabetes.Clinical diabetes : a publication of the American Diabetes Association · 2022
    Article
  17. Article
  18. Nutritional basis of type 2 diabetes remission.BMJ (Clinical research ed.) · 2021
    Article
  19. The obesity paradox and diabetes.Eating and weight disorders : EWD · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jennifer LogueInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom. jennifer.logue@glasgow.ac.uk
Jeremy J Walker
Graham Leese
Robert Lindsay
John McKnight
Andrew Morris
Sam Philip
Sarah Wild
Naveed Sattar
Scottish Diabetes Research Network Epidemiology Group

Funding

Wellcome Trust 090532Wellcome Trust WT086113
6 · The paper itself

Abstract

objectiveTo describe the association of BMI with mortality in patients diagnosed with type 2 diabetes. RESEARCH DESIGN AND

methodsUsing records of 106,640 patients in Scotland, we investigated the association between BMI recorded around the diagnosis of type 2 diabetes mellitus (T2DM) and mortality using Cox proportional hazards regression adjusted for age and smoking status, with BMI 25 to <30 kg/m(2) as a referent group. Deaths within 2 years of BMI determination were excluded. Mean follow-up to death or the end of 2007 was 4.7 years.

resultsA total of 9,631 deaths occurred between 2001 and 2007. Compared with the reference group, mortality risk was higher in patients with BMI 20 to <25 kg/m(2) (hazard ratio 1.22 [95% CI 1.13-1.32] in men, 1.32 [1.22-1.44] in women) and patients with BMI ≥35 kg/m(2) (for example, 1.70 [1.24-2.34] in men and 1.81 [1.46-2.24] in women for BMI 45 to <50 kg/m(2)). Vascular mortality was higher for each 5-kg/m(2) increase in BMI >30 kg/m(2) by 24% (15-35%) in men and 23% (14-32%) in women, but was lower below this threshold. The results were similar after further adjustment for HbA1c, year of diagnosis, lipids, blood pressure, and socioeconomic status.

conclusionsPatients categorized as normal weight or obese with T2DM within a year of diagnosis of T2DM exhibit variably higher mortality outcomes compared with the overweight group, confirming a U-shaped association of BMI with mortality. Whether weight loss interventions reduce mortality in all T2DM patients requires study.

Indexed as

Body Mass IndexDiabetes Mellitus, Type 2FemaleHumansMaleOverweightProportional Hazards ModelsSex Factors

Identifiers

PMID23139375
PMCPMC3609520

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.