ArticleMagma (New York, N.Y.)2013
Magnetization transfer for the assessment of bowel fibrosis in patients with Crohn's disease: initial experience.
Article in Magma (New York, N.Y.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it.
- An expert consensus to standardise definitions, diagnosis and treatment targets for anti-fibrotic stricture therapies in Crohn's disease.Alimentary pharmacology & therapeutics · 2018Pooled it
- Pancreas Volume Declines During the First Year After Diagnosis of Type 1 Diabetes and Exhibits Altered Diffusion at Disease Onset.Diabetes care · 2019Trial
- Phenotype-driven management in ileocecal Crohn's disease: a narrative review with a proposed research framework.Therapeutic advances in gastroenterology · 2026Review
- Fibrosis: cross-organ biology and pathways to development of innovative drugs.Nature reviews. Drug discovery · 2025Review
- Quantitative Magnetic Resonance Imaging (qMRI) of the Small Bowel in Crohn's Disease: State-of-the-Art and Future Directions.Journal of magnetic resonance imaging : JMRI · 2025Review
- Multiomics reveals microbial metabolites as key actors in intestinal fibrosis in Crohn's disease.EMBO molecular medicine · 2024Article
- Combined Use of Magnetization Transfer Ratio and T2-Mapping to Evaluate Extraocular Muscle Pathophysiology in Myasthenia Gravis with Ophthalmoparesis.International journal of medical sciences · 2024Article
- MRI texture analysis of T2-weighted images is preferred over magnetization transfer imaging for readily longitudinal quantification of gut fibrosis.European radiology · 2023Article
- How to Evaluate Fibrosis in IBD?Diagnostics (Basel, Switzerland) · 2023Review
- Role of abbreviated non-contrast-enhanced MR-enterography in the evaluation of Crohn's disease activity and complications as an alternative for full protocol contrast-enhanced study: A systematic review and meta-analysis.Research in diagnostic and interventional imaging · 2023Article
- Magnetic Resonance Enterography and Histology in Patients With Fibrostenotic Crohn's Disease: A Multicenter Study.Clinical and translational gastroenterology · 2022Article
- Cross-Sectional Imaging Instead of Colonoscopy in Inflammatory Bowel Diseases: Lights and Shadows.Journal of clinical medicine · 2022Review
- Test-retest assessment of non-contrast MRI sequences to characterise and quantify the small bowel wall in healthy participants.Magma (New York, N.Y.) · 2021Article
- Quantitative Magnetic Resonance Imaging in Perianal Crohn's Disease at 1.5 and 3.0 T: A Feasibility Study.Diagnostics (Basel, Switzerland) · 2021Article
- NativeBiosensors · 2021Article
- Comparison of Three Magnetization Transfer Ratio Parameters for Assessment of Intestinal Fibrosis in Patients with Crohn's Disease.Korean journal of radiology · 2020Article
- Characterization of Degree of Intestinal Fibrosis in Patients with Crohn Disease by Using Magnetization Transfer MR Imaging.Radiology · 2018Article
- Magnetisation transfer as a biomarker for chronic airway fibrosis in a mouse lung transplantation model.European radiology experimental · 2018Article
- Advanced imaging techniques for small bowel Crohn's disease: what does the future hold?Therapeutic advances in gastroenterology · 2018Review
- Imaging of the small intestine in Crohn's disease: Joint position statement of the Indian Society of Gastroenterology and Indian Radiological and Imaging Association.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2017Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectTo assess the feasibility of magnetization transfer (MT) imaging of the bowel wall in patients with Crohn's disease (CD), and to evaluate its utility for the detection of intestinal fibrosis. MATERIALS AND
methodsIn this prospective study, 31 patients (age 39.0 ± 13.2 years) with CD were examined in a 1.5T MR scanner. To establish a standard of reference, two independent readers classified the patients in different disease states using standard MR enterography, available clinical data and histological findings. In addition to the standard protocol, a 2D gradient-echo sequence (TR/TE 32 ms/2.17 ms; flip angle 25°) with/without 1,100 Hz off-resonance prepulse was applied. MT ratios (MTR) of the small bowel wall were computed off-line on a pixel-by-pixel basis.
resultsThe MT sequences acquired images of sufficient quality and spatial resolution for the evaluation of the small bowel wall without detrimental motion artefacts. In normal bowel wall segments, an intermediate MTR of 25.4 ± 3.4 % was measured. The MTR was significantly increased in bowel wall segments with fibrotic scarring (35.3 ± 4.0 %, p < 0.0001). In segments with acute inflammation, the mean MTR was slightly smaller (22.9 ± 2.2 %).
conclusionMT imaging of the small bowel wall is feasible in humans with sufficient image quality and may help with the identification of fibrotic scarring in patients with CD.
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Registered trials
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