Evidence map›Paper›PMID 23137071›Full record

ArticlePain medicine (Malden, Mass.)2012

The association of depression with pain-related treatment utilization in patients with multiple sclerosis.

Kevin N Alschuler, Mark P Jensen, Dawn M Ehde

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Pain medicine (Malden, Mass.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03782246 (Mindfulness-based Cognitive Therapy and Cognitive Behavioral Therapy for Chronic Pain in Multiple Sclerosis), which is not on this map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03782246 naunknown statusnot on this mapstarted 2018, after this paper: background citation

Mindfulness-based Cognitive Therapy and Cognitive Behavioral Therapy for Chronic Pain in Multiple Sclerosis

TypeinterventionalSponsorUniversity of WashingtonRan2018 to 2022Enrolled273ConditionsMultiple SclerosisArmsMBCT, CBT
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Co-occurring depression and pain in multiple sclerosis.Physical medicine and rehabilitation clinics of North America · 2013
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kevin N AlschulerDepartment of Rehabilitation Medicine, University of Washington School of Medicine, Seattle, WA 98104, USA. kalschul@uw.edu
Mark P Jensen
Dawn M Ehde
University of Washington · US

Funding

SURVEY AND LONGITUDINAL STUDIES OF SECONDARY PAINP01HD033988 · NICHD · UNIVERSITY OF WASHINGTON · PI JENSEN, MARK P · 1996 to 2006
$4.8M
NICHD NIH HHS P01 HD033988NICHD NIH HHS P01 HD33988
6 · The paper itself

Abstract

objectiveTo better understand the association of depression with pain treatment utilization in a multiple sclerosis (MS) population.

designCross-sectional survey.

settingCommunity-based survey.

participantsConvenience sample of 117 individuals with MS.

main outcome measuresParticipants provided demographic information, descriptive information on utilization of pain treatments, pain intensity ratings on a 0-10 numerical rating scale, and depressive symptoms on the Patient Health Questionnaire-9 (PHQ-9).

resultsParticipants reporting clinical levels of depressive symptoms (PHQ-9 ≥10) reported that they tried more pain treatments previously relative to participants with PHQ-9 <10; however, the two groups did not differ in the number of treatments they were currently using. Additionally, participants with PHQ-9 ≥10 had more visits to providers for pain treatment relative to the group with PHQ-9 <10. In subsequent analyses, results showed that these differences were no longer significant after controlling for level of pain intensity.

conclusionsThe results demonstrate that depression is not associated with higher pain treatment utilization. These findings support the assertion in previous studies that the mechanism by which depression impacts medical utilization is through increased appointments for nonspecific complaints, not for specific medical problems. While this suggests that treating depression may not be helpful in reducing pain treatment utilization specifically, it remains important to treat depression to reduce pain-related suffering and medical utilization more broadly.

Indexed as

Chronic PainDepressionMultiple SclerosisAdultAgedCross-Sectional StudiesDepressive DisorderFemaleHumansMaleMiddle AgedPain ManagementPain MeasurementRegression AnalysisSeverity of Illness IndexSurveys and Questionnaires

Identifiers

PMID23137071
PMCPMC3527650
OpenAlexW1507729040

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.