Malaria vaccine trials--beyond efficacy end points.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

9 citing papers in PubMed.

1. Mosquirix™ RTS, S/AS01 Vaccine Development, Immunogenicity, and Efficacy.Vaccines · 2022
   Review
2. Towards Eradication of Malaria: Is the WHO's RTS,S/AS01 Vaccination Effective Enough?Risk management and healthcare policy · 2021
   Review
3. Efficacy of phase 3 trial of RTS, S/AS01 malaria vaccine: The need for an alternative development plan.Human vaccines & immunotherapeutics · 2017
   Article
4. Malaria Vaccines: Moving Forward After Encouraging First Steps.Current tropical medicine reports · 2015
   Article
5. Biomarkers of safety and immune protection for genetically modified live attenuated leishmania vaccines against visceral leishmaniasis - discovery and implications.Frontiers in immunology · 2014
   Review
6. Bacterially expressed full-length recombinant Plasmodium falciparum RH5 protein binds erythrocytes and elicits potent strain-transcending parasite-neutralizing antibodies.Infection and immunity · 2014
   Article
7. Whole Pichia pastoris yeast expressing measles virus nucleoprotein as a production and delivery system to multimerize Plasmodium antigens.PloS one · 2014
   Article
8. The utility of Plasmodium berghei as a rodent model for anti-merozoite malaria vaccine assessment.Scientific reports · 2013
   Article
9. Malaria in infants aged less than six months - is it an area of unmet medical need?Malaria journal · 2012
   Review

Corrections and comments

• Comment on
  A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants.2012

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as