Evidence map›Paper›PMID 23136538›Full record

Trial reportInternational journal of medical sciences2012

Multiple-, but not single-, dose of parecoxib reduces shoulder pain after gynecologic laparoscopy.

Hufei Zhang, Haihua Shu, Lu Yang, Minghui Cao, Jingjun Zhang, Kexuan Liu, Liangcan Xiao, Xuyu Zhang

2 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in International journal of medical sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01843010 phase4completednot on this mapstarted 2013, after this paper: background citation

Effect of Parecoxib on the Change of Shoulder Pain Threshold After Gynecological Laparoscopies

TypeinterventionalSponsorFirst Affiliated Hospital, Sun Yat-Sen UniversityRan2013 to 2013Enrolled140ConditionsPostoperative Pain Management, Pain Threshold, Shoulder Pain, LaparoscopiesArmsParecoxib, Placebo
NCT05344677 nacompletednot on this mapstarted 2022, after this paper: background citation

Effect Of Trendelenburg Position, Warm Pad Application and Deep Breathing Exercise on Shoulder Pain and Post Gynecologic Laparoscopic Recovery

TypeinterventionalSponsorAlexandria UniversityRan2022 to 2022Enrolled90ConditionsGynecologic Nursing, Postoperative PainArmsTrendelenburg Position, Warm Pad Application, Deep Breathing Exercise
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Time Characteristics of Shoulder Pain after Laparoscopic Surgery.JSLS : Journal of the Society of Laparoendoscopic Surgeons
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Hufei ZhangDepartment of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Haihua Shu
Lu Yang
Minghui Cao
Jingjun Zhang
Kexuan Liu
Liangcan Xiao
Xuyu Zhang
Sun Yat-sen University · CNThe First Affiliated Hospital, Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to investigate effect of single- and multiple-dose of parecoxib on shoulder pain after gynecologic laparoscopy.

methods126 patients requiring elective gynecologic laparoscopy were randomly allocated to three groups. Group M (multiple-dose): receiving parecoxib 40mg at 30min before the end of surgery, at 8 and 20hr after surgery, respectively; Group S (single-dose): receiving parecoxib 40mg at 30min before the end of surgery and normal saline at the corresponding time points; Group C (control): receiving normal saline at the same three time points. The shoulder pain was evaluated, both at rest and with motion, at postoperative 6, 24 and 48hr. The impact of shoulder pain on patients' recovery (activity, mood, walking and sleep) was also evaluated. Meanwhile, rescue analgesics and complications were recorded.

resultsThe overall incidence of shoulder pain in group M (37.5%) was lower than that in group C (61.9%) (difference=-24.4%; 95% CI: 3.4~45.4%; P=0.023). Whereas, single-dose regimen (61.0%) showed no significant reduction (difference with control=-0.9%; 95% CI: -21.9~20.0%; P=0.931). Moreover, multiple-dose regimen reduced the maximal intensity of shoulder pain and the impact for activity and mood in comparison to the control. Multiple-dose of parecoxib decreased the consumption of rescue analgesics. The complications were similar among all groups and no severe complications were observed.

conclusionsMultiple-, but not single-, dose of parecoxib may attenuate the incidence and intensity of shoulder pain and thereby improve patients' quality of recovery following gynecologic laparoscopy.

Indexed as

AdultAnalgesicsDrug Administration ScheduleFemaleGynecologic Surgical ProceduresHumansIsoxazolesLaparoscopyPain MeasurementPostoperative PainShoulder PainTreatment OutcomeAnalgesicsIsoxazolesparecoxiblaparoscopic surgerynonsteroidal anti-inflammatory drugspostoperative painShoulder pain

Identifiers

PMID23136538
PMCPMC3491434
OpenAlexW2127038842

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.