Evidence map›Paper›PMID 23135991›Full record

ReviewJournal of cardiovascular translational research2013

Endothelial dysfunction and cardiac allograft vasculopathy.

Monica Colvin-Adams, Nonyelum Harcourt, Daniel Duprez

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of cardiovascular translational research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Article
  6. Article
  7. Failing Heart Transplants and Rejection-A Cellular Perspective.Journal of cardiovascular development and disease · 2021
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Testing the Efficacy of Contrast-Enhanced Ultrasound in Detecting Transplant Rejection Using a Murine Model of Heart Transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2017
    Article
  14. Observational
  15. Role of Transient Receptor Potential Channels in Heart Transplantation: A Potential Novel Therapeutic Target for Cardiac Allograft Vasculopathy.Medical science monitor : international medical journal of experimental and clinical research · 2017
    Review
  16. Rac1 Pharmacological Inhibition Rescues Human Endothelial Dysfunction.Journal of the American Heart Association · 2017
    Article
  17. Article
  18. Article
  19. Article
  20. Cardiac allograft vasculopathy: a donor or recipient induced pathology?Journal of cardiovascular translational research · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Monica Colvin-AdamsCardiovascular Division, University of Minnesota, Minneapolis, MN 55455, USA. Colvi005@umn.edu
Nonyelum Harcourt
Daniel Duprez

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac allograft vasculopathy remains a major challenge to long-term survival after heart transplantation. Endothelial injury and dysfunction, as a result of multifactorial immunologic and nonimmunologic insults in the donor and the recipient, are prevalent early after transplant and may be precursors to overt cardiac allograft vasculopathy. Current strategies for managing cardiac allograft vasculopathy, however, rely on the identification and treatment of established disease. Improved understanding of mechanisms leading to endothelial dysfunction in heart transplant recipients may provide the foundation for the development of sensitive screening techniques and preventive therapies.

Indexed as

AnimalsCoronary Artery DiseaseCoronary VesselsEndothelium, VascularGraft SurvivalHeart TransplantationHumansTreatment OutcomeVascular System Injuries

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.