ArticleInternational journal of clinical pharmacy2013
An audit of prophylactic surgical antibiotic use in a Sudanese Teaching Hospital.
Article in International journal of clinical pharmacy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 35 citations in OpenAlex.
- Antibiotic usage in surgical prophylaxis: surveillance of clean and clean-contaminated surgeries in a tertiary care hospital.Frontiers in public health · 2026Observational
- Characteristics and antibiotic resistance patterns of urinary tract isolates in hospitalized and non-hospitalized patients: a cross-sectional study in Khartoum, Sudan.BMC infectious diseases · 2024Article
- Prevalence and risk factors of post-cholecystectomy surgical site infections.Annals of medicine and surgery (2012) · 2023Article
- Review of antibiotic prescriptions as part of antimicrobial stewardship programmes: results from a pilot implementation at two provincial-level hospitals in Viet Nam.JAC-antimicrobial resistance · 2023Article
- Antibiotic Usage in Patients Having Undergone Caesarean Section: A Three-Level Study in Benin.Antibiotics (Basel, Switzerland) · 2022Article
- Effect of Antibiotic Prophylaxis on Surgical Site Infection in Thyroid and Parathyroid Surgery: A Systematic Review and Meta-Analysis.Antibiotics (Basel, Switzerland) · 2022Review
- Assessment of implementation of antibiotic stewardship program in surgical prophylaxis at a secondary care hospital in Ras Al Khaimah, United Arab Emirates.Scientific reports · 2021Article
- Supporting global antimicrobial stewardship: antibiotic prophylaxis for the prevention of surgical site infection in low- and middle-income countries (LMICs): a scoping review and meta-analysis.JAC-antimicrobial resistance · 2020Article
- Evaluation of Surgical Antimicrobial Prophylaxis and Incidence of Surgical Site Infection at Borumeda Hospital, Northeast Ethiopia: Retrospective Cross-Sectional Study.Drug, healthcare and patient safety · 2020Article
- Knowledge, attitude and practice of surgical staff towards preoperative surgical antibiotic prophylaxis at an academic tertiary hospital in Sudan.Patient safety in surgery · 2019Article
- In transition: current health challenges and priorities in Sudan.BMJ global health · 2019Review
- Antibiotic utilization pattern for surgical site infection prophylaxis at Dil Chora Referral Hospital Surgical Ward, Dire Dawa, Eastern Ethiopia.BMC research notes · 2018Article
- Article
- Antibiotic usage in surgical prophylaxis: A prospective observational study in the surgical ward of Nekemte referral hospital.PloS one · 2018Observational
- An antibiotic audit of the surgical department at a rural hospital in Western Kenya.The Pan African medical journal · 2018Article
- Article
- An observational study of perioperative antibiotic-prophylaxis use at a major quaternary care and referral hospital in Saudi Arabia.Saudi journal of anaesthesiaArticle
- An Audit of Perioperative Antimicrobial Prophylaxis: Compliance with the International Guidelines.Journal of research in pharmacy practiceArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAntibiotic prophylaxis is effective at reducing the risk of postoperative infection for nearly all types of surgery. Objective To audit the use of prophylactic antibiotics for elective surgery.
settingKhartoum Teaching Hospital, Sudan, a 1,000 bed tertiary level hospital.
methodA prospective study was conducted over a 9 month period; patients admitted for elective surgery were included consecutively.
main outcome measureThe use and administration of prophylactic antibiotics for elective surgery.
resultsA total of 1,768 patients with mean age 37.8 ± 14 years were recruited (females, 83.3 % of total) who underwent 1,814 surgical interventions. Of these 1,277 (70.4 %) of procedures were clean-contaminated. A total of 1,758 patients (99.4 % of total) received antibiotics for prophylaxis; 1,730 patients (97.9 %) were given antibiotics in the operating room; for 1,288 (74.5 %) of cases the antibiotics were considered 'recommended', while for 442 (25.5 %) they were not. Out of the patients for whom prophylaxis was recommended and was given, 725 (56.3 %) of patients received a broad spectrum antibiotic or unnecessary combination, 913 (70.9 %) received a sub-therapeutic dose, 120 (9.3 %) were given the first preoperative dose within the proper time window, and 1,250 (97 %) of patients had an extended duration of prophylaxis. Compliance with all stated criteria was achieved in only 47 (2.7 %) of observed prescriptions.
conclusionThis audit showed a wide gap between international standards and local practices; the authors call for urgent action to correct this situation through the development and implementation of local clinical guidelines.
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