Evidence map›Paper›PMID 23135729›Full record

ArticleJournal of virology2013

Lethal canine distemper virus outbreak in cynomolgus monkeys in Japan in 2008.

Kouji Sakai, Noriyo Nagata, Yasushi Ami, Fumio Seki, Yuriko Suzaki, Naoko Iwata-Yoshikawa, Tadaki Suzuki, Shuetsu Fukushi, Tetsuya Mizutani, Tomoki Yoshikawa and 8 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed, 2 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 2 syntheses or guidelines pooled it, 141 citations in OpenAlex.

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  17. Antiviral activity of nitazoxanide againstJournal of virus eradication · 2023
    Article
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32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 2 institutions in 1 country.

Kouji SakaiDepartment of Virology III, National Institute of Infectious Diseases, Tokyo, Japan.
Noriyo Nagata
Yasushi Ami
Fumio Seki
Yuriko Suzaki
Naoko Iwata-Yoshikawa
Tadaki Suzuki
Shuetsu Fukushi
Tetsuya Mizutani
Tomoki Yoshikawa
Noriyuki Otsuki
Ichiro Kurane
Katsuhiro Komase
Ryoji Yamaguchi
Hideki Hasegawa
Masayuki Saijo
Makoto Takeda
Shigeru Morikawa
National Institute of Infectious Diseases · JPUniversity of Miyazaki · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Canine distemper virus (CDV) has recently expanded its host range to nonhuman primates. A large CDV outbreak occurred in rhesus monkeys at a breeding farm in Guangxi Province, China, in 2006, followed by another outbreak in rhesus monkeys at an animal center in Beijing in 2008. In 2008 in Japan, a CDV outbreak also occurred in cynomolgus monkeys imported from China. In that outbreak, 46 monkeys died from severe pneumonia during a quarantine period. A CDV strain (CYN07-dV) was isolated in Vero cells expressing dog signaling lymphocyte activation molecule (SLAM). Phylogenic analysis showed that CYN07-dV was closely related to the recent CDV outbreaks in China, suggesting continuing chains of CDV infection in monkeys. In vitro, CYN07-dV uses macaca SLAM and macaca nectin4 as receptors as efficiently as dog SLAM and dog nectin4, respectively. CYN07-dV showed high virulence in experimentally infected cynomolgus monkeys and excreted progeny viruses in oral fluid and feces. These data revealed that some of the CDV strains, like CYN07-dV, have the potential to cause acute systemic infection in monkeys.

Indexed as

Disease OutbreaksAnimalsChinaChlorocebus aethiopsCluster AnalysisDistemperDistemper Virus, CanineFecesMacaca fascicularisMacaca mulattaMolecular Sequence DataPhylogenyPrimate DiseasesRNA, ViralSalivaSequence Analysis, DNARNA, Viral

Identifiers

PMID23135729
PMCPMC3554058
OpenAlexW1972949627

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.