Evidence map›Paper›PMID 23135724›Full record

ArticleJournal of virology2013

Characterization of the nonstructural proteins of the bocavirus minute virus of canines.

Loretta Sukhu, Olufemi Fasina, Lisa Burger, Ayushi Rai, Jianming Qiu, David J Pintel

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Loretta SukhuDepartment of Molecular Microbiology and Immunology, University of Missouri-Columbia School of Medicine, Columbia, MO, USA.
Olufemi Fasina
Lisa Burger
Ayushi Rai
Jianming Qiu
David J Pintel
University of Missouri · USUniversity of Kansas Medical Center · US

Funding

Parvovirus RNA Processing and Gene Expression StrategiesR01AI046458 · NIAID · UNIVERSITY OF MISSOURI-COLUMBIA · PI PINTEL, DAVID J. · 2000 to 2018
$4.6M
Post-Transcriptional Regulation of Parvovirus Capsid Gene ExpressionR01AI070723 · NIAID · UNIVERSITY OF KANSAS MEDICAL CENTER · PI QIU, JIANMING · 2007 to 2017
$3.3M
Molecular characterization of the bocavirusesR21AI085236 · NIAID · UNIVERSITY OF KANSAS MEDICAL CENTER · PI QIU, JIANMING · 2010 to 2011
$411k
Parvovirus RNA Processing and Gene Expression StrategiesR56AI046458 · NIAID · UNIVERSITY OF MISSOURI-COLUMBIA · PI PINTEL, DAVID J. · 2013 to 2013
$374k
Post-Transcriptional Regulation of Parvovirus Capsid Gene ExpressionR56AI070723 · NIAID · UNIVERSITY OF KANSAS MEDICAL CENTER · PI QIU, JIANMING · 2006 to 2006
$290k
NIAID NIH HHS AI 046458NIAID NIH HHS AI070723NIAID NIH HHS AI 085236NIAID NIH HHS R01 AI046458NIAID NIH HHS R01 AI070723NIAID NIH HHS R21 AI085236NIAID NIH HHS R56 AI046458NIAID NIH HHS R56 AI070723
6 · The paper itself

Abstract

We present a detailed characterization of a single-cycle infection of the bocavirus minute virus of canines (MVC) in canine WRD cells. This has allowed identification of an additional smaller NS protein that derives from an mRNA spliced within the NS gene that had not been previously reported. In addition, we have identified a role for the viral NP1 protein during infection. NP1 is required for read-through of the MVC internal polyadenylation site and, thus, access of the capsid gene by MVC mRNAs. Although the mechanism of NP1's action has not yet been fully elucidated, it represents the first parvovirus protein to be implicated directly in viral RNA processing.

Indexed as

AnimalsBase SequenceBocavirusCell LineDogsMolecular Sequence DataRNA, MessengerRNA SplicingViral Nonstructural ProteinsRNA, MessengerViral Nonstructural Proteins

Identifiers

PMID23135724
PMCPMC3554049
OpenAlexW2122513948

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.