Evidence map›Paper›PMID 23133824›Full record

ArticleAmerican journal of nuclear medicine and molecular imaging2012

Current neuroimaging techniques in Alzheimer's disease and applications in animal models.

Linda Zhang, Raymond Chuen-Chung Chang, Leung-Wing Chu, Henry Ka-Fung Mak

Abstract read
In one paragraph

Article in American journal of nuclear medicine and molecular imaging, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Fully automated radiosynthesis of [American journal of nuclear medicine and molecular imaging · 2024
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  3. Automated radiosynthesis of [American journal of nuclear medicine and molecular imaging · 2024
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  4. Automated radiosynthesis of [American journal of nuclear medicine and molecular imaging · 2023
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  5. Article
  6. Automated production of [American journal of nuclear medicine and molecular imaging · 2021
    Article
  7. Article
  8. Insight into the Molecular Imaging of Alzheimer's Disease.International journal of biomedical imaging · 2016
    Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Multimodality imaging of RNA interference.Current medicinal chemistry · 2013
    Review
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Linda ZhangDepartment of Diagnostic Radiology, The University of Hong Kong HKSAR.
Raymond Chuen-Chung Chang
Leung-Wing Chu
Henry Ka-Fung Mak

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With Alzheimer's disease (AD) quickly becoming the most costly disease to society, and with no disease-modifying treatment currently, prevention and early detection have become key points in AD research. Important features within this research focus on understanding disease pathology, as well as finding biomarkers that can act as early indicators and trackers of disease progression or potential treatment. With the advances in neuroimaging technology and the development of new imaging techniques, the search for cheap, noninvasive, sensitive biomarkers becomes more accessible. Modern neuroimaging techniques are able to cover most aspects of disease pathology, including visualization of senile plaques and neurofibrillary tangles, cortical atrophy, neuronal loss, vascular damage, and changes in brain biochemistry. These methods can provide complementary information, resulting in an overall picture of AD. Additionally, applying neuroimaging to animal models of AD could bring about greater understanding in disease etiology and experimental treatments whilst remaining in vivo. In this review, we present the current neuroimaging techniques used in AD research in both their human and animal applications, and discuss how this fits in to the overall goal of understanding AD.

Indexed as

Alzheimer’s diseaseanimal modelsASLbiomarkersMRIMRSneuroimagingPET

Identifiers

PMID23133824
PMCPMC3477739

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.