ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2013
Molecular diagnosis of bacterial vaginosis: impact on IVF outcome.
Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- The Role of Genital Tract Microbiome in Fertility: A Systematic Review.International journal of molecular sciences · 2021Pooled it
- The Role of the Genital Tract Microbiome in Human Fertility: A Literature Review.Journal of clinical medicine · 2025Review
- Microbiome-Maternal Tract Interactions in Women with Recurrent Implantation Failure.Microorganisms · 2025Review
- Effect of Waiting Period on Initial Adverse Vaginal Microbiome Composition in IVF-ICSI Patients.Journal of clinical medicine · 2024Article
- Association between bacterial vaginosis, Chlamydia trachomatis infection and tubal factor infertility in Bukavu, Democratic Republic of Congo.BMC infectious diseases · 2024Article
- Assessing vaginal microbiome through Vaginal Microecology Evaluation System as a predictor forFrontiers in endocrinology · 2024Article
- Female reproductive tract microbiome and early miscarriages.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2023Review
- Genital Microbiota and Outcome of Assisted Reproductive Treatment-A Systematic Review.Life (Basel, Switzerland) · 2022Review
- The Association between Vaginal Dysbiosis and Reproductive Outcomes in Sub-Fertile Women Undergoing IVF-Treatment: A Systematic PRISMA Review and Meta-Analysis.Pathogens (Basel, Switzerland) · 2021Review
- When a Neonate Is Born, So Is a Microbiota.Life (Basel, Switzerland) · 2021Review
- Association of the Cervical Microbiota With Pregnancy Outcome in a Subfertile Population UndergoingFrontiers in cellular and infection microbiology · 2021Article
- Characterization of the Vaginal Microbiome in Women with Infertility and Its Potential Correlation with Hormone Stimulation duringmSystems · 2020Article
- The ReceptIVFity cohort study protocol to validate the urogenital microbiome as predictor for IVF or IVF/ICSI outcome.Reproductive health · 2018Article
- Impact of asymptomatic genital tract infections on in vitro Fertilization (IVF) outcome.PloS one · 2018Article
- Risk factors for bacterial vaginosis: results from a cross-sectional study having a sample of 53,652 women.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2014Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacterial vaginosis can increase obstetrical complications such as miscarriage, premature rupture of membranes and preterm delivery. The aim of our study was first to assess BV prevalence for infertile patients treated by in vitro fertilisation (IVF) using both the Nugent score and polymerase chain reaction (PCR), and then to assess the impact of BV on the pregnancy rate after IVF. Vaginal samples were obtained from women followed for IVF in our Assisted Reproduction Technology (ART) Unit between August 2010 and April 2011. For each patient, two techniques were performed to diagnose BV: Gram staining to assess the Nugent score and a quantitative molecular analysis using a specific real-time PCR assay. Two groups were studied: normal flora (BV-) and BV (BV+). The primary outcome measure was the implantation rate. The secondary outcomes were clinical pregnancy rate, early and late miscarriage, premature rupture of membranes, preterm delivery, mode of delivery and birthweight. A total of 307 patients were included. PCR revealed a prevalence of BV of 9.45 %. Among women who performed vaginal douching, 22.2 % were BV+, whereas 7.9 % of patients who did not douche were BV+ (p = 0.028). The embryo implantation rate was decreased between the BV- and BV+ groups (36.3 % vs. 27.6 %, p = 0.418), but it was not significant. Obstetrical outcomes did not present significant statistical differences among the groups. Vaginal douching significantly enhanced BV in women treated with IVF. We also observed a non-significant decrease of embryo implantation rate and clinical pregnancy rate for women treated by IVF.
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